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ARHGAP4 gene

Known as: Rho-GAP hematopoietic protein C1, RGC1, p115 
National Institutes of Health

Papers overview

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2020
2020
Comprehensive analysis on the whole Rho‐GAP family reveals that ARHGAP4 suppresses EMT in epithelial cells under negative regulation by Septin9
Epithelial to mesenchymal transition (EMT) is a fundamental biological process that occurs during development and tumorigenesis… 
2019
2019
ARHGAP4 mediates the Warburg effect in pancreatic cancer through the mTOR and HIF-1α signaling pathways
Objective The phenomenon that cancer cells avidly exhibit glycolysis with lactate secretion and decrease in mitochondrial… 
2017
2017
Pathway and network-based analysis of genome-wide association studies and RT-PCR validation in polycystic ovary syndrome
The purpose of this study was to identify promising candidate genes and pathways in polycystic ovary syndrome (PCOS). Microarray… 
Review
2012
Review
2012
A novel contiguous gene deletion of AVPR2 and ARHGAP4 genes in male dizygotic twins with nephrogenic diabetes insipidus and intellectual disability
The clinical features of loss of ARHGAP4 function remain unclear despite several reports of different patterns of deletions… 
Highly Cited
2007
Highly Cited
2007
ARHGAP4 is a novel RhoGAP that mediates inhibition of cell motility and axon outgrowth
2007
2007
Gene expression profiles of erythroid precursors characterise several mechanisms of the action of hydroxycarbamide in sickle cell anaemia
Hydroxycarbamide (HC) (or hydroxyurea) has been reported to increase fetal haemoglobin levels and improve clinical symptoms in… 
2006
2006
Severe combined immunodeficiency associated with nephrogenic diabetes insipidus and a deletion in the Xq28 region.
2004
2004
Identification and characterization of ARHGAP27 gene in silico.
ARHGAP1, ARHGAP2, ARHGAP3, ARHGAP4, ARHGAP5, ARHGAP6, ARHGAP7 (DLC1), ARHGAP8, ARHGAP9, ARHGAP10, ARHGAP12, ARHGAP13 (SRGAP1… 
2003
2003
Identification of p115 as a PLCgamma1-binding protein and the role of Src homology domains of PLCgamma1 in the vesicular transport.
In order to gain further insight into the function(s) of PLCgamma1, we tried to identify the binding partners that can interact… 
2001
2001
Possible implication of the Golgi apparatus casein kinase in the phosphorylation of vesicle docking protein p115 Ser-940: a study with peptide substrates.
Phosphorylation of human vescicle docking protein p115 at Ser-942 (homologous to Ser-940 in rat p115) promotes its dissociation… 
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