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ARHGAP4 gene

Known as: Rho-GAP hematopoietic protein C1, RGC1, p115 
National Institutes of Health

Papers overview

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2020
2020
Comprehensive analysis on the whole Rho‐GAP family reveals that ARHGAP4 suppresses EMT in epithelial cells under negative regulation by Septin9
Epithelial to mesenchymal transition (EMT) is a fundamental biological process that occurs during development and tumorigenesis… 
2019
2019
ARHGAP4 mediates the Warburg effect in pancreatic cancer through the mTOR and HIF-1α signaling pathways
Objective The phenomenon that cancer cells avidly exhibit glycolysis with lactate secretion and decrease in mitochondrial… 
Highly Cited
2012
Highly Cited
2012
Proteomic Profiling of the TRAF3 Interactome Network Reveals a New Role for the ER-to-Golgi Transport Compartments in Innate Immunity
Tumor Necrosis Factor receptor-associated factor-3 (TRAF3) is a central mediator important for inducing type I interferon (IFN… 
2012
2012
Identification of a functional domain within the p115 tethering factor that is required for Golgi ribbon assembly and membrane trafficking
Summary The tethering factor p115 (known as Uso1p in yeast) has been shown to facilitate Golgi biogenesis and membrane traffic in… 
Review
2012
Review
2012
A novel contiguous gene deletion of AVPR2 and ARHGAP4 genes in male dizygotic twins with nephrogenic diabetes insipidus and intellectual disability
The clinical features of loss of ARHGAP4 function remain unclear despite several reports of different patterns of deletions… 
Highly Cited
2007
Highly Cited
2007
ARHGAP4 is a novel RhoGAP that mediates inhibition of cell motility and axon outgrowth
2006
2006
Severe combined immunodeficiency associated with nephrogenic diabetes insipidus and a deletion in the Xq28 region.
2004
2004
Identification and characterization of ARHGAP27 gene in silico.
  • Y. KatohM. Katoh
  • International Journal of Molecular Medicine
  • 2004
  • Corpus ID: 2986882
ARHGAP1, ARHGAP2, ARHGAP3, ARHGAP4, ARHGAP5, ARHGAP6, ARHGAP7 (DLC1), ARHGAP8, ARHGAP9, ARHGAP10, ARHGAP12, ARHGAP13 (SRGAP1… 
2002
2002
Cloning of rat ARHGAP4/C1, a RhoGAP family member expressed in the nervous system that colocalizes with the Golgi complex and microtubules.
2001
2001
Possible implication of the Golgi apparatus casein kinase in the phosphorylation of vesicle docking protein p115 Ser-940: a study with peptide substrates.
Phosphorylation of human vescicle docking protein p115 at Ser-942 (homologous to Ser-940 in rat p115) promotes its dissociation… 
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