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ARF6 gene

Known as: ADP ribosylation factor 6, ADP-RIBOSYLATION FACTOR 6, ARF6 
National Institutes of Health

Papers overview

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2013
2013
ARF6-Regulated Endocytosis of Growth Factor Receptors Links Cadherin-Based Adhesion to Canonical Wnt Signaling in Epithelia
ABSTRACT Wnt signaling has an essential role in embryonic development as well as stem/progenitor cell renewal, and its aberrant… 
Highly Cited
2012
Highly Cited
2012
MICAL‐L1 is a Tubular Endosomal Membrane Hub that Connects Rab35 and Arf6 With Rab8a
Endocytosis is a conserved process across species in which cell surface receptors and lipids are internalized from the plasma… 
Highly Cited
2006
Highly Cited
2006
Endogenous ARF6 interacts with Rac1 upon angiotensin II stimulation to regulate membrane ruffling and cell migration.
ARF6 and Rac1 are small GTPases known to regulate remodelling of the actin cytoskeleton. Here, we demonstrate that these… 
Highly Cited
2005
Highly Cited
2005
An effector domain mutant of Arf6 implicates phospholipase D in endosomal membrane recycling.
In this study, we investigated the role of phospholipase D (PLD) in mediating Arf6 function in cells. Expression of Arf6 mutants… 
Highly Cited
2001
Highly Cited
2001
Specificities for the Small G Proteins ARF1 and ARF6 of the Guanine Nucleotide Exchange Factors ARNO and EFA6*
ARF1 and ARF6 are distant members of the ADP-ribosylation factor (ARF) small G-protein subfamily. Their distinct cellular… 
Highly Cited
2001
Highly Cited
2001
Gα11 Signaling through ARF6 Regulates F-Actin Mobilization and GLUT4 Glucose Transporter Translocation to the Plasma Membrane
ABSTRACT The action of insulin to recruit the intracellular GLUT4 glucose transporter to the plasma membrane of 3T3-L1 adipocytes… 
Highly Cited
1999
Highly Cited
1999
ADP-ribosylation Factor 6 as a Target of Guanine Nucleotide Exchange Factor GRP1*
The GRP1 protein contains a Sec7 homology domain that catalyzes guanine nucleotide exchange on ADP-ribosylation factors (ARF) 1… 
Highly Cited
1999
Highly Cited
1999
ARF6 Is Required for Growth Factor- and Rac-Mediated Membrane Ruffling in Macrophages at a Stage Distal to Rac Membrane Targeting
ABSTRACT Activation of Rac1, a member of the Rho family of GTPases, is associated with multiple cellular responses, including… 
Highly Cited
1998
Highly Cited
1998
Subcellular Distribution and Differential Expression of Endogenous ADP-ribosylation Factor 6 in Mammalian Cells*
ADP-ribosylation factor (ARF) 6 has been shown to play a role in vesicular transport; however, the expression and subcellular… 
Highly Cited
1997
Highly Cited
1997
Regulated Exocytosis in Chromaffin Cells
The ADP-ribosylation factor (ARF) GTP-binding proteins are believed to function as regulators of vesicular budding and fusion… 
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