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ARF1 gene

Known as: ADP ribosylation factor 1, ADP-RIBOSYLATION FACTOR 1, ARF1 
 
National Institutes of Health

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ADP-Ribosylation Factor 1

Papers overview

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2017
2017
9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments
COPI coated vesicles mediate trafficking within the Golgi apparatus and between the Golgi and the endoplasmic reticulum. Assembly… Expand
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2016
2016
ARF1 promotes prostate tumorigenesis via targeting oncogenic MAPK signaling
ADP-ribosylation factor 1 (ARF1) is a crucial regulator in vesicle-mediated membrane trafficking and involved in the activation… Expand
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2015
2015
ARF1 regulates adhesion of MDA-MB-231 invasive breast cancer cells through formation of focal adhesions.
Adhesion complex formation and disassembly is crucial for maintaining efficient cell movement. During migration, several proteins… Expand
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2014
2014
The Adaptor Proteins p66Shc and Grb2 Regulate the Activation of the GTPases ARF1 and ARF6 in Invasive Breast Cancer Cells*
Background: ADP-ribosylation factors (ARF) 1 and 6 play an important role in breast cancer cell proliferation, migration, and… Expand
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Highly Cited
2013
Highly Cited
2013
Recruitment of PI4KIIIβ to Coxsackievirus B3 Replication Organelles Is Independent of ACBD3, GBF1, and Arf1
ABSTRACT Members of the Enterovirus (poliovirus [PV], coxsackieviruses, and human rhinoviruses) and Kobuvirus (Aichi virus… Expand
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2013
2013
AMPK phosphorylates GBF1 for mitotic Golgi disassembly
Summary In mammalian cells, the Golgi apparatus undergoes extensive fragmentation during mitosis; this is required not only for… Expand
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2013
2013
ARF1 controls Rac1 signaling to regulate migration of MDA-MB-231 invasive breast cancer cells.
ADP-ribosylation factors (ARFs) are monomeric G proteins that regulate many cellular processes such as reorganization of the… Expand
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2005
2005
Mutational Analysis of the Arf1•GTP/Arf GAP Interface Reveals an Arf1 Mutant that Selectively Affects the Arf GAP ASAP1
Arf1 is a GTP binding protein that functions at a number of cellular sites to control membrane traffic and actin remodeling. Arf1… Expand
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Highly Cited
2001
Highly Cited
2001
Multiple roles of Arf1 GTPase in the yeast exocytic and endocytic pathways.
ADP-ribosylation factors, a family of small GTPases, are believed to be key regulators of intracellular membrane traffic. However… Expand
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Highly Cited
1994
Highly Cited
1994
Expression of a dominant allele of human ARF1 inhibits membrane traffic in vivo
ADP-ribosylation factor (ARF) proteins and inhibitory peptides derived from ARFs have demonstrated activities in a number of in… Expand
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