Xiaoyue Pan

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Light and food are two major environmental factors that impact daily life. Light entrainment is centrally controlled by suprachiasmatic nuclei of the hypothalamus. Food entrainment might require cooperation between the intestine and dorsomedial hypothalamus. Clock genes that are essential for light entrainment also play a part in food entrainment.(More)
In mammals, most physiological, biochemical, and behavioral processes show a circadian rhythm. In the present study, we examined the diurnal rhythm of the H+-peptide cotransporter (PEPT1), which transports small peptides and peptide-like drugs in the small intestine and kidney, using rats maintained in a 12-h photoperiod with free access to chow. The(More)
We previously demonstrated that H+/peptide cotransporter PEPT1 shows a diurnal rhythm in the rat small intestine. In the present study, we examined the effect of food intake on the diurnal rhythm of intestinal PEPT1 using fed and fasted rats and also determined whether such variation affected the pharmacokinetics of peptide-like drugs. In fed rats, PEPT1(More)
We develop an analytical modeling framework for efficient prediction of cache miss ratios based on reuse distance distributions. The only input needed for our predictions is the reuse distance distribution of a program execution: previous work has shown that they can be obtained with very small overhead by sampling from native executions. This should be(More)
While maintaining the coherency of private caches, invalidation-based cache coherence protocols introduce cache coherence misses. We address the problem of predicting the number of cache coherence misses in the private cache of a parallel application when running on a multicore system with an invalidation-based cache coherence protocol. We propose three new(More)
The microbial fuel cell (MFC) was evaluated as an alternative way to recover electricity from canteen based food waste. Characteristics of the organics in food waste before and after the MFC treatment were analyzed to investigate how the organic matters were biodegraded and transformed during the MFC treatment. A maximum power density of 5.6W/m(3) and an(More)
Using constraint-based local search, we effectively model and efficiently solve the problem of balancing the traffic demands on portions of the European airspace while ensuring that their capacity constraints are satisfied. The traffic demand of a portion of airspace is the hourly number of flights planned to enter it, and its capacity is the upper bound on(More)
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