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AR-C239

Known as: ARC 239, AR C239, AR-C 239 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Adrenergic alpha-AntagonistsIsoquinolinesPiperazines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Dexmedetomidine Protects Rat Liver against Ischemia-Reperfusion Injury Partly by the α2A-Adrenoceptor Subtype and the Mechanism Is Associated with the TLR4/NF-κB Pathway
Toll-like receptor 4 (TLR4)/nuclear factor kappa B (NF-κB) signaling plays a dominant role in the pathogenesis of liver ischemia… 
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2007
2007
Crystal structure of glutathione reductase Glr1 from the yeast Saccharomyces cerevisiae
Yeast glutathione (GSH) reductase Glr1 is a dimeric flavo‐oxidoreductase involved in cytoplasmic and mitochondrial redox… 
2004
2004
Alpha-2 agonist-induced memory impairment is mediated by the alpha-2A-adrenoceptor subtype
The activation of alpha2-adrenoceptors has been reported to impair memory functions in both rats and humans. The alpha2… 
Highly Cited
2002
Highly Cited
2002
Alcohol-Induced c-Fos Expression in the Edinger-Westphal Nucleus: Pharmacological and Signal Transduction Mechanisms
Mapping inducible transcription factors has shown that the Edinger-Westphal nucleus is preferentially sensitive to alcohol… 
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Highly Cited
2000
Highly Cited
2000
Silent alpha(2C)-adrenergic receptors enable cold-induced vasoconstriction in cutaneous arteries.
Cold constricts cutaneous blood vessels by increasing the reactivity of smooth muscle alpha(2)-adrenergic receptors (alpha(2)-ARs… 
Highly Cited
1996
Highly Cited
1996
Different alpha-adrenoceptor subtypes mediate constriction of arterioles and venules.
Recent studies indicate that rat vascular smooth muscle can express mRNAs for the alpha 1A-(alpha 1c-), alpha 1B-, alpha 1D… 
1992
1992
Characterization of prejunctional alpha-2 adrenergic receptors involved in modulation of adrenergic transmitter release in the isolated perfused rat kidney.
The subclassification of alpha-2 adrenergic receptors into A and B subtypes is based on radioligand binding and functional… 
Highly Cited
1990
Highly Cited
1990
Involvement of alpha-2 adrenergic receptor subtypes in hyperglycemia.
Alpha-2 adrenoceptor stimulation induces in the mouse a hyperglycemic response which is accompanied by a concomitant inhibition… 
Highly Cited
1989
Highly Cited
1989
Alpha-2A and alpha-2B adrenergic receptor subtypes: attenuation of cyclic AMP production in cell lines containing only one receptor subtype.
At least two subtypes of alpha-2 adrenergic receptors have been identified on the basis of antagonist affinities as determined… 
Highly Cited
1988
Highly Cited
1988
Alpha-2A and alpha-2B adrenergic receptor subtypes: antagonist binding in tissues and cell lines containing only one subtype.
The affinities of 34 adrenergic antagonists for alpha-2 adrenergic receptors were determined from homogenate radioligand binding… 
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