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AR-C239

Known as: ARC 239, AR C239, AR-C 239 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Adrenergic alpha-AntagonistsIsoquinolinesPiperazines

Papers overview

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2007
2007
Crystal structure of glutathione reductase Glr1 from the yeast Saccharomyces cerevisiae
Yeast glutathione (GSH) reductase Glr1 is a dimeric flavo‐oxidoreductase involved in cytoplasmic and mitochondrial redox… 
2001
2001
Effect of dexmedetomidine on the release of [3H]-noradrenaline from rat kidney cortex slices: characterization of α2-adrenoceptor
2000
2000
Functional evidence that gastroprotection can be induced by activation of central alpha(2B)-adrenoceptor subtypes in the rat.
1996
1996
[3H]2-(2-Benzofuranyl)-2-imidazoline, a highly selective radioligand for I2-imidazoline receptor binding sites Studies in rabbit kidney membranes
Abstract 2-(2-Benzofuranyl)-2-imidazoline (2-BFI) has recently been characterised as a selective ligand for the I2-type of… 
1992
1992
Characterization of prejunctional alpha-2 adrenergic receptors involved in modulation of adrenergic transmitter release in the isolated perfused rat kidney.
The subclassification of alpha-2 adrenergic receptors into A and B subtypes is based on radioligand binding and functional… 
1990
1990
Functional characterization of neuronal pre and postsynaptic α2‐adrenoceptor subtypes in guinea‐pig submucosal plexus
1 The α2‐adrenoceptors on cell bodies of submucosal neurones, on presynaptic cholinergic nerve terminals innervating submucosal… 
1988
1988
Mouse monoclonal antibodies for experimental immunotherapy promotes killing of tumor cells
Monoclonal antibodies (MAbs) produced against a human colon adenocarcinoma cell line, Colo‐205, were tested in antibody‐dependent… 
1987
1987
The blood pressure effects of alpha-adrenoceptor antagonists injected in the medullary site of action of clonidine: the nucleus reticularis lateralis.
1985
1985
Effects of clonidine on neuronal firing evoked by a noxious stimulus
1980
1980
Pharmacological properties of AR-C239, 2-[2-[4(o-methoxyphenyl)-piperazine-1-Yl]-ethyl]4,4-dimethyl-1,3(2H-4H) isoquinolinedione, a new alpha-adrenoceptor blocking drug.
In pentobarbital-treated dogs and rats, AR-C239, a new and potent alpha-adrenoceptor blocking drug, competitively antagonized… 
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