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AR 12463

Known as: AR-12463, Ethanol, 2-(pentyl(5-(1-piperidinyl)(1,2,4)triazolo(1,5-a)pyrimidin-7-yl)amino)- 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Trapidil
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
[The use of lymphocyte cultures for the investigation of drug biotransformation].
In the present paper the rat lymphocytes and mouse myeloma cell culture are developed as in vitro test systems and used for the… 
1991
1991
Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits.
Daily administration of the trapidil derivative AR 12463 (20 mg/kg body weight i.p.) to cholesterol-fed rabbits diminished… 
1991
1991
[Improvement of the disolution behavior of problem drugs. 22. Preformulations of AR 12463 in absorption models].
1988
1988
Influence of the antianginal drug trapidil and its derivative AR 12463 on arachidonic acid liberation and thromboxane formation in thrombin-stimulated platelets.
The 5,7-disubstituted s-triazolo(1,5-a)pyrimidines (TPs) trapidil and AR 12463 inhibited the thrombin-induced Thromboxane (TX… 
1988
1988
Effect of derivatives of trapidil on the expression of LDL receptors.
The influence of trapidil and some of its derivatives (AR 12456, AR 12463, AR 12465) on the LDL receptor mediated uptake and… 
1987
1987
Trapidil derivatives as potential antiatherosclerotic drugs.
Trapidil, a triazolopyrimidine, and its derivatives are coronary vasodilating drugs. Trapidil reduces the serum level of low… 
1987
1987
[The effect of trapidil and the trapidil derivative AR 12463 on blood pressure and thromboxane formation in spontaneously hypertensive rats].
The trapidil derivative AR 12463 has a much more stronger inhibiting effect than trapidil on different atherosclerotic parameters… 
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