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APOBEC-1 Deaminase

Known as: HEPR Protein, APOBEC-1, APOBEC-1 Protein 
An APOBEC deaminase catalytic subunit of the apolipoprotein B (APOB) MESSENGER RNA (mRNA) editing enzyme complex that is involved in post… 
National Institutes of Health

Related topics

Related topics

9 relations
APOBEC1 geneIn BloodProcess of secretionantagonists & inhibitors

Broader (1)

Apolipoprotein B mRNA Editing Enzyme

Papers overview

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Highly Cited
2016
Highly Cited
2016
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
APOBEC-catalyzed cytosine-to-uracil deamination of single-stranded DNA (ssDNA) has beneficial functions in immunity and… 
Highly Cited
2005
Highly Cited
2005
Antiviral Function of APOBEC3G Can Be Dissociated from Cytidine Deaminase Activity
Highly Cited
2000
Highly Cited
2000
Molecular Cloning of Apobec-1 Complementation Factor, a Novel RNA-Binding Protein Involved in the Editing of Apolipoprotein B mRNA
ABSTRACT The C-to-U editing of apolipoprotein B (apo-B) mRNA is catalyzed by a multiprotein complex that recognizes an 11… 
Highly Cited
2000
Highly Cited
2000
Purification and Molecular Cloning of a Novel Essential Component of the Apolipoprotein B mRNA Editing Enzyme-Complex*
Editing of apolipoprotein B (apoB) mRNA requires the catalytic component APOBEC-1 together with “auxiliary” proteins that have… 
Review
1999
Review
1999
Transgenic rabbits as models for atherosclerosis research.
Several characteristics of the rabbit make it an excellent model for the study of lipoprotein metabolism and atherosclerosis. New… 
Highly Cited
1997
Highly Cited
1997
Cloning of an Apobec-1-binding Protein That Also Interacts with Apolipoprotein B mRNA and Evidence for Its Involvement in RNA Editing*
Apolipoprotein (apo)B mRNA editing is mediated by a multiprotein editosome complex. Apobec-1 is the catalytic component of this… 
Review
1997
Review
1997
Mammalian RNA-dependent deaminases and edited mRNAs.
Highly Cited
1996
Highly Cited
1996
Targeted Disruption of the Mouse apobec-1 Gene Abolishes Apolipoprotein B mRNA Editing and Eliminates Apolipoprotein B48 (*)
A site-specific C to U editing reaction modifies nuclear apolipoprotein B100 (apoB100) mRNA, producing apolipoprotein B48 in the… 
Highly Cited
1996
Highly Cited
1996
Overexpression of APOBEC-1 Results in Mooring Sequence-dependent Promiscuous RNA Editing (*)
Apolipoprotein B (apoB) RNA editing involves site-specific deamination of a cytidine to a uridine. A mooring sequence, a spacer… 
Highly Cited
1995
Highly Cited
1995
Mutagenesis of apobec-1, the Catalytic Subunit of the Mammalian Apolipoprotein B mRNA Editing Enzyme, Reveals Distinct Domains That Mediate Cytosine Nucleoside Deaminase, RNA Binding, and RNA Editing…
Apolipoprotein (apo) B48 is synthesized by mammalian small intestine as a result of post-transcriptional RNA editing. This… 
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