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APOBEC-1 Deaminase

Known as: HEPR Protein, APOBEC-1, APOBEC-1 Protein 
An APOBEC deaminase catalytic subunit of the apolipoprotein B (APOB) MESSENGER RNA (mRNA) editing enzyme complex that is involved in post… 
National Institutes of Health

Related topics

Related topics

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APOBEC1 geneIn BloodProcess of secretionantagonists & inhibitors

Broader (1)

Apolipoprotein B mRNA Editing Enzyme

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Metabolic regulation of ApoB mRNA editing is associated with phosphorylation of APOBEC-1 complementation factor
Apolipoprotein B (apoB) mRNA editing is a nuclear event that minimally requires the RNA substrate, APOBEC-1 and APOBEC-1… 
2004
2004
Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression.
BACKGROUND & AIMS This study aimed to determine the role of the RNA binding protein apobec-1 in radioprotection of the intestine… 
2004
2004
Identification of Novel Alternative Splice Variants of APOBEC-1 Complementation Factor with Different Capacities to Support Apolipoprotein B mRNA Editing*
Two novel mRNA transcripts have been identified that result from species- and tissue-specific, alternative polyadenylation and… 
2001
2001
Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome.
ApoB mRNA editing is mediated by an editosome complex with apobec-1 as its catalytic component. By yeast two-hybrid cloning using… 
Review
2000
Review
2000
Apolipoprotein B: from editosome to proteasome.
Apolipoprotein (apo) B, the protein component of low-density lipoproteins (LDLs), has been under intense investigation for the… 
1999
1999
Absence of APOBEC-1 mediated mRNA editing in human carcinomas
The transgene expression of the catalytic subunit APOBEC-1 of the apo B mRNA editing enzyme-complex can cause hepatocellular… 
Highly Cited
1998
Highly Cited
1998
Two Efficiency Elements Flanking the Editing Site of Cytidine 6666 in the Apolipoprotein B mRNA Support Mooring-dependent Editing*
Normally, apolipoprotein B (apoB) mRNA editing deaminates a single cytidine (C6666) in apoB mRNA. However, when the catalytic… 
Highly Cited
1998
Highly Cited
1998
A Sequence-Specific RNA-Binding Protein Complements Apobec-1 To Edit Apolipoprotein B mRNA
ABSTRACT The editing of apolipoprotein B (apo-B) mRNA involves the site-specific deamination of cytidine to uracil. The… 
Review
1997
Review
1997
Mammalian RNA-dependent deaminases and edited mRNAs.
1995
1995
Proposed nomenclature for the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme: APOBEC-1.
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