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APLN gene

Known as: APJ RECEPTOR LIGAND, APLN, XNPEP2 
This gene is involved in the regulation of both immune responses and HIV-1 infection.
National Institutes of Health

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APLN wt Allele
ApelinImmune responseIntercellular Communication Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
A short review of adipokines, smooth muscle and uterine contractility.
Review
2014
Review
2014
The control of insulin secretion by adipokines: current evidence for adipocyte-beta cell endocrine signalling in metabolic homeostasis
Metabolic homeostasis is maintained by the coordinated action of multiple organ systems. Insulin secretion is often enhanced… 
2014
2014
Cardioprotective effects of adipokine apelin on myocardial infarction
Angiogenesis plays an important role in myocardial infarction. Apelin and its natural receptor (angiotensin II receptor-like 1… 
2012
2012
A role for endothelial cells in promoting the maturation of astrocytes through the apelin/APJ system in mice
Interactions between astrocytes and endothelial cells (ECs) are crucial for retinal vascular formation. Astrocytes induce… 
Highly Cited
2011
Highly Cited
2011
Apelin-transgenic mice exhibit a resistance against diet-induced obesity by increasing vascular mass and mitochondrial biogenesis in skeletal muscle.
2010
2010
Effect of sinus rhythm restoration after electrical cardioversion on apelin and brain natriuretic Peptide prohormone levels in patients with persistent atrial fibrillation.
Highly Cited
2010
Highly Cited
2010
Liquid chromatography/tandem mass spectrometry assay for the absolute quantification of the expected circulating apelin peptides in human plasma.
Apelin peptides are of great interest owing to their involvement in physiological and pathological processes and they have been… 
2009
2009
Plasma apelin levels in obstructive sleep apnea and the effect of continuous positive airway pressure therapy.
Apelin is a peptide hormone with cardiovascular and glucose homeostasis properties, and obstructive sleep apnea (OSA) is… 
Highly Cited
2006
Highly Cited
2006
Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis.
Highly Cited
2006
Highly Cited
2006
Reduced apelin levels in lone atrial fibrillation.
AIMS Apelin is an endogenous peptide hormone that appears to have a physiological role in counter-regulation of the angiotensin… 
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