APLN gene

Known as: APJ RECEPTOR LIGAND, APLN, XNPEP2 
This gene is involved in the regulation of both immune responses and HIV-1 infection.
National Institutes of Health

Papers overview

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Review
2015
Review
2015
Obesity increases the risk for metabolic, cardiovascular, chronic inflammatory, and several malignant diseases and, therefore… (More)
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Highly Cited
2011
Highly Cited
2011
Growing evidence supports the role of gut microbiota in the development of obesity, type 2 diabetes, and low-grade inflammation… (More)
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Highly Cited
2010
Highly Cited
2010
Obesity, the most common nutritional disorder in industrialized countries, is associated with an increased mortality and… (More)
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Highly Cited
2008
Highly Cited
2008
Adipose tissue (AT) secretes several adipokines that influence insulin sensitivity and potentially link obesity to insulin… (More)
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Highly Cited
2008
Highly Cited
2008
Systematic efforts to understand membrane protein stability under a variety of different solution conditions are not widely… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES This study sought to explore the role of new biomarkers in heart failure (HF). BACKGROUND We investigated the… (More)
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Highly Cited
2002
Highly Cited
2002
The orphan receptor APJ and its recently identified endogenous ligand, apelin, exhibit high levels of mRNA expression in the… (More)
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Highly Cited
2000
Highly Cited
2000
We have recently identified apelin as the endogenous ligand for human APJ. In rats, the highest expression of APJ mRNA was… (More)
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Highly Cited
2000
Highly Cited
2000
The human APJ receptor is a G protein-coupled receptor which functions as an efficient alternative co-receptor for a number of… (More)
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Highly Cited
1999
Highly Cited
1999
By using a strategy that we have developed to search for the ligands of orphan seven-transmembrane-domain receptors [S. Hinuma et… (More)
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