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APLN gene

Known as: APJ RECEPTOR LIGAND, APLN, XNPEP2 
This gene is involved in the regulation of both immune responses and HIV-1 infection.
National Institutes of Health

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APLN wt Allele
ApelinImmune responseIntercellular Communication Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Metabolic effects of obesity: A review.
With the many recent advances in the biomedical world, vast changes are taking place in our growing knowledge of the… 
Review
2008
Review
2008
The apelin-APJ system in heart failure: pathophysiologic relevance and therapeutic potential.
Highly Cited
2007
Highly Cited
2007
Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis.
Highly Cited
2007
Highly Cited
2007
The g protein-coupled receptor agtrl1b regulates early development of myocardial progenitors.
Highly Cited
2007
Highly Cited
2007
Apelin and its receptor control heart field formation during zebrafish gastrulation.
Highly Cited
2006
Highly Cited
2006
Down-regulation of cardiac apelin system in hypertrophied and failing hearts: Possible role of angiotensin II-angiotensin type 1 receptor system.
Highly Cited
2004
Highly Cited
2004
Regulatory Roles for APJ, a Seven-transmembrane Receptor Related to Angiotensin-type 1 Receptor in Blood Pressure in Vivo*
APJ is a G-protein-coupled receptor with seven transmembrane domains, and its endogenous ligand, apelin, was identified recently… 
Highly Cited
2001
Highly Cited
2001
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain
Apelin, a peptide recently isolated from bovine stomach tissue extracts, has been identified as the endogenous ligand of the… 
Highly Cited
2000
Highly Cited
2000
Molecular and Functional Characteristics of APJ
We have recently identified apelin as the endogenous ligand for human APJ. In rats, the highest expression of APJ mRNA was… 
Highly Cited
1999
Highly Cited
1999
Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum.
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