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Apelin

Known as: AGTRL1 Ligand, APJ Endogenous Ligand, APLN 
Apelin (77 aa, ~9 kDa) is encoded by the human APLN gene. This protein is involved in both the inhibition of HIV-1 entry into cells and in immune… 
National Institutes of Health

Related topics

Related topics

6 relations
APLN geneApelin:MCnc:Pt:Ser/Plas:QnBrainHuman Colostrum

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Role of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders
Apelin, a (neuro)vasoactive peptide, plays a prominent role in controlling body fluid homeostasis and cardiovascular functions… 
Highly Cited
2013
Highly Cited
2013
Effects of Dietary Eicosapentaenoic Acid (EPA) Supplementation in High-Fat Fed Mice on Lipid Metabolism and Apelin/APJ System in Skeletal Muscle
Various studies have shown that eicosapentaenoic acid (EPA) has beneficial effects on obesity and associated disorders. Apelin… 
Highly Cited
2012
Highly Cited
2012
Apelin Enhances Cardiac Neovascularization After Myocardial Infarction by Recruiting Aplnr+ Circulating Cells
Rationale: Neovascularization stimulated by local or recruited stem cells after ischemia is a key process that salvages damaged… 
Highly Cited
2012
Highly Cited
2012
APELIN promotes hematopoiesis from human embryonic stem cells.
Transcriptional profiling of differentiating human embryonic stem cells (hESCs) revealed that MIXL1-positive mesodermal… 
2012
2012
A role for endothelial cells in promoting the maturation of astrocytes through the apelin/APJ system in mice
Interactions between astrocytes and endothelial cells (ECs) are crucial for retinal vascular formation. Astrocytes induce… 
Highly Cited
2011
Highly Cited
2011
Apelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells
Vascular calcification, which results from a process osteoblastic differentiation of vascular smooth muscle cells (VSMCs), is a… 
Highly Cited
2010
Highly Cited
2010
Liquid chromatography/tandem mass spectrometry assay for the absolute quantification of the expected circulating apelin peptides in human plasma.
Apelin peptides are of great interest owing to their involvement in physiological and pathological processes and they have been… 
2010
2010
Apelin: A potential link between inflammation and cardiovascular disease in end stage renal disease patients
Abstract Background and objectives. Cardiovascular disease is the leading cause of morbidity and mortality in hemodialysis… 
2008
2008
Visfatin and apelin, new adipocytokines, and their relation to endothelial function in patients with chronic renal failure.
PURPOSE Visfatin and apelin are novel adipocytokines that have recently generated much interest. The aim of the study was to… 
Highly Cited
2006
Highly Cited
2006
Reduced apelin levels in lone atrial fibrillation.
AIMS Apelin is an endogenous peptide hormone that appears to have a physiological role in counter-regulation of the angiotensin… 
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