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Apelin

Known as: AGTRL1 Ligand, APJ Endogenous Ligand, APLN 
Apelin (77 aa, ~9 kDa) is encoded by the human APLN gene. This protein is involved in both the inhibition of HIV-1 entry into cells and in immune… 
National Institutes of Health

Related topics

Related topics

6 relations
APLN geneApelin:MCnc:Pt:Ser/Plas:QnBrainHuman Colostrum

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Role of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders
Apelin, a (neuro)vasoactive peptide, plays a prominent role in controlling body fluid homeostasis and cardiovascular functions… 
2013
2013
Apelin acts in the subfornical organ to influence neuronal excitability and cardiovascular function
•  Apelin receptor mRNA is expressed in the subfornical organ. •  Apelin influences the excitability of the majority of… 
Highly Cited
2012
Highly Cited
2012
Apelin Enhances Cardiac Neovascularization After Myocardial Infarction by Recruiting Aplnr+ Circulating Cells
Rationale: Neovascularization stimulated by local or recruited stem cells after ischemia is a key process that salvages damaged… 
Highly Cited
2012
Highly Cited
2012
APELIN promotes hematopoiesis from human embryonic stem cells.
Transcriptional profiling of differentiating human embryonic stem cells (hESCs) revealed that MIXL1-positive mesodermal… 
2012
2012
A role for endothelial cells in promoting the maturation of astrocytes through the apelin/APJ system in mice
Interactions between astrocytes and endothelial cells (ECs) are crucial for retinal vascular formation. Astrocytes induce… 
Highly Cited
2010
Highly Cited
2010
Liquid chromatography/tandem mass spectrometry assay for the absolute quantification of the expected circulating apelin peptides in human plasma.
Apelin peptides are of great interest owing to their involvement in physiological and pathological processes and they have been… 
2010
2010
Apelin: A potential link between inflammation and cardiovascular disease in end stage renal disease patients
Abstract Background and objectives. Cardiovascular disease is the leading cause of morbidity and mortality in hemodialysis… 
2009
2009
Plasma apelin levels in obstructive sleep apnea and the effect of continuous positive airway pressure therapy.
Apelin is a peptide hormone with cardiovascular and glucose homeostasis properties, and obstructive sleep apnea (OSA) is… 
2008
2008
Visfatin and apelin, new adipocytokines, and their relation to endothelial function in patients with chronic renal failure.
PURPOSE Visfatin and apelin are novel adipocytokines that have recently generated much interest. The aim of the study was to… 
Highly Cited
2006
Highly Cited
2006
Reduced apelin levels in lone atrial fibrillation.
AIMS Apelin is an endogenous peptide hormone that appears to have a physiological role in counter-regulation of the angiotensin… 
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