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API 2

Known as: API-2 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Chlorpropamide
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Abstract 261: The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition
API-1 is a novel small molecule inhibitor of Akt, which acts by binding to Akt and preventing its membrane translocation, and has… 
2012
2012
Award Number: W81XWH-08-1-0453 TITLE: Development of Mouse Models of Ovarian Cancer for Studying Tumor Biology and Testing Novel Molecularly Targeted Therapeutic Strategies. PRINCIPAL INVESTIGATOR:
Purpose: Genetically engineered mouse (GEM) models of ovarian cancer that closely recapitulate their human tumor counterparts may… 
2012
2012
Abstract 1863: The multifunconal role of B7-H3 in metastasis and drug resistance
With the advent of new targeted therapeutic alternatives some encouraging therapeutic improvements have been achieved. However… 
2011
2011
Abstract 4845: Tumor cell line profiling of eighteen cancer therapeutics to evaluate relationships between tumor genotypes and cancer cell sensitivities
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL In vitro cellular response profiling of tumor human… 
2010
2010
Abstract LB-40: Inhibition of anchorage-independent growth of melanoma cell lines using Riluzole in combination with PI3 kinase pathway inhibitors
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC We previously reported that the majority of human… 
2009
2009
A Probe into the Mechanism of Inhibitive Growth of SGC7901 Treated with API-2
Objective To study the expression of p-AKT in gastric cancer cells SGC7901 treated with Akt Inhibitor Ⅱ(API-2) and the growth… 
2007
2007
Combined inhibition of Cdk9 and AKT induces apoptosis of metastatic prostate cancer cells
5399 Prostate cancer (PCa) is one of the most common malignancies in humans and the second leading cause of male cancer death in… 
2001
2001
Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues.
2001
2001
Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues.
1998
1998
Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues.
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