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Chlorpropamide

Known as: Urea, 1-((p-chlorophenyl)sulfonyl)-3-propyl-, Benzenesulfonamide, 4-chloro-N-((propylamino)carbonyl)-, Clorpropamida 
A long-acting, first-generation sulfonylurea with hypoglycemic activity. Compared to other sulfonylureas, chlorpropamide has an increased risk of… 
National Institutes of Health

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23 relations

Narrower (6)

2-hydroxychlorpropamideAPI 2DiabineseGlucamide
Chlorpropamide:MCnc:24H:Urine:QnChlorpropamide:PrThr:Pt:Ser/Plas:OrdChlorpropamide:PrThr:Pt:XXX:OrdDiabetes Mellitus, Insulin-Dependent

Broader (2)

Hypoglycemic AgentsSulfonylurea Compounds

Papers overview

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1986
1986
Chlorpropamide Raises Fructose-2,6-Bisphosphate Concentration and Inhibits Gluconeogenesis in Isolated Rat Hepatocytes
The addition of chlorpropamide to hepatocytes isolated from fed rats raised the cellular concentration of fructose-2,6… 
1985
1985
2-[(4-Azido-2-nitrophenyl)amino]ethyl triphosphate, a novel chromophoric and photoaffinity analogue of ATP. Synthesis, characterization, and interaction with myosin subfragment 1.
A facile and high-yield synthesis of a new ATP analogue, 2-[(4-azido-2-nitrophenyl)amino]ethyl triphosphate (NANTP), is described… 
1984
1984
Acute hemolytic anemia associated with a chlorpropamide‐induced apparent auto‐anti‐Jka
A patient with acute hemolytic anemia and a positive direct antiglobulin test was found to be Jk(a + b +) with anti‐Jka in her… 
1979
1979
Hepatic Effects of Chlorpropamide: Inhibition of Glucagon-stimulated Gluconeogenesis in Perfused Livers of Fasted Rats
In perfused livers of rats fasted for 24 h, glucagon (5 × 10−10 M) significantly elevated tissue and perfusate levels of cyclic… 
Highly Cited
1977
Highly Cited
1977
Potentiation of the Hepatic Action of Insulin by Chlorpropamide
In perfused livers of fed rats, chlorpropamide inhibits glucagon-stimulated glucose production by augmenting the action of… 
1970
1970
Gas Chromatographic Method for Determination of Tolbutamide and Chlorpropamide
Gas-liquid chromatographic methods for the measurement of tolbutamide and chlorpropamide in blood and urine and in pharmaceutical… 
Highly Cited
1968
Highly Cited
1968
The pattern of rsponse of plasma insulin and glucose to meals and fasting during chlorpropamide therapy.
Abstract Frequent determinations of insulin and glucose were done in a group of obese diabetics during a 48-hr test period… 
Highly Cited
1968
Highly Cited
1968
Hypernatremia due to hypodipsia and elevated threshold for vasopressin release. Effects of treatment with hydrochlorothiazide, chlorpropamide and tolbutamide.
Abstract A woman previously operated for craniopharyngioma has chronic hypernatremia without polyuria or polydipsia. The… 
1968
1968
Antidiuretic effect of 1-propyl-3-p-chlorobenzene-sulfonylurea (chlorpropamide).
Abstract It was found that in addition to its hypoglycemic action 1-propyl-3-p-chlorobenzene- sulfonylurea has an antidiuretic… 
Highly Cited
1967
Highly Cited
1967
Potentiation of acetohexamide hypoglycemia by phenylbutazone.
PROLONGED and profound hypoglycemia has occasionally been reported in patients who have been taking the sulfonylurea agents.1 2 3…