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ANO1 wt Allele

Known as: TMEM16A, ORAOV2, Anoctamin 1, Calcium Activated Chloride Channel wt Allele 
Human ANO1 wild-type allele is located in the vicinity of 11q13.3 and is approximately 111 kb in length. This allele, which encodes anoctamin-1… 
National Institutes of Health

Related topics

Related topics

6 relations
11q13.3Homo sapiensIonophore activityLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The Natural Compound Cinnamaldehyde is a Novel Activator of Calcium-Activated Chloride Channel
Calcium-activated chloride channels (CaCCs) play important roles in a multitude of physiological processes, and in many cells… 
2016
2016
Coupling of TRPV6 and TMEM16A in epithelial principal cells of the rat epididymis
Principal cells regulate the ionic environment of the epididymal lumen via unknown mechanisms. Gao et al. use… 
2016
2016
Pulmonary , gastrointestinal and urogenital pharmacology Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways
Defective epithelial chloride secretion occurs in humans with cystic fibrosis (CF), a genetic defect due to loss of function of… 
2015
2015
Identification of the Novel TMEM16A Inhibitor Dehydroandrographolide and Its Anticancer Activity on SW620 Cells
TMEM16A, a calcium-activated chloride channel (CaCC), is highly amplified and expressed in human cancers and is involved in the… 
2015
2015
Sweating chloride bullets: understanding the role of calcium in eccrine sweat glands and possible implications for hyperhidrosis
Eccrine (atrichial) sweat glands are large, active cutaneous endorgans vital to human thermal and fluid homeostasis, but regional… 
2014
2014
Non-canonical translation start sites in the TMEM16A chloride channel
2014
2014
Prognostic significance of TMEM16A, PPFIA1, and FADD expression in invasive ductal carcinoma of the breast
Background11q13 region is a frequently amplified locus in human malignancies. Among the genes located in this region, FADD is one… 
Review
2011
Review
2011
Role of the Ca2+-activated Cl- channels bestrophin and anoctamin in epithelial cells
Abstract Two families of proteins, the bestrophins (Best) and the recently cloned TMEM16 proteins (anoctamin, Ano), recapitulate… 
Review
2009
Review
2009
Pancreatic Expression of DOG1: A Novel Gastrointestinal Stromal Tumor (GIST) Biomarker
The cDNA microarray gene profile of gastrointestinal stromal tumors (GISTs) revealed that DOG1 (TMEM16A) gene was mostly… 
2004
2004
Identification and characterization of TMEM16E and TMEM16F genes in silico.
TMEM16A (FLJ10261 or ORAOV2) gene within the CCND1-FGF4-EMS1 amplicon at human chromosome 11q13.3 encodes transmembrane protein… 
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