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ANG1005

Known as: ANG-1005 
National Institutes of Health

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Related topics

2 relations
GRN1005

Broader (1)

paclitaxel-Angiopep-2 conjugate

Papers overview

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2016
2016
Abstract P6-17-04: A phase II, open-label, multi-center study of ANG1005, a novel brain-penetrant taxane derivative, in breast cancer patients with recurrent CNS metastases
Background: Treatment options for brain metastases are limited to local therapies due to the inability of most anti-cancer agents… 
2015
2015
ANG1005 for brain metastases from breast cancer: 18F-FLT-PET and MRI as complementary approaches to response assessment.
2552 Background: ANG1005 is a novel drug conjugate consisting of 3 molecules of paclitaxel covalently linked to Angiopep-2… 
2015
2015
SESSION 2 : DRUG DELIVERY P 2 . 01 ANG-1005 in Patients with Brain Metastases from Breast Cancer : Correlative Imaging with 18 F-FLT-PET / CT
2014
2014
Evaluation of CNS and peripheral antitumor activity of ANG1005 in patients with brain metastases from breast tumors and other advanced solid tumors.
2523 Background: ANG1005 consists of 3 paclitaxel molecules covalently linked to a proprietary 19 AA peptide that targets the… 
2013
2013
Abstract B76: A phase II study of ANG1005, a novel, brain-penetrant taxane derivative, in breast cancer patients with brain metastases.
Background: Treatment for brain metastases is an unmet medical need. ANG1005 consists of 3 paclitaxels covalently linked to a… 
2013
2013
Abstract P6-11-05: ANG4043, a brain-penetrant anti-HER2 mAb increases survival in mice bearing intracranial BT-474 breast tumor cells
Background: Treatment options for metastatic brain tumors originating from HER2-positive breast disease are limited due to the… 
2010
2010
Abstract 4417: Uptake of the new paclitaxel-derivative (ANG1005) by the low-density lipoprotein receptor-related protein1 (LRP1) is related to the aggressive phenotype of glioblastoma cells
The most common primary brain tumour is glioblastoma multiforme (GBM). Despite latest cancer researches to improve the outcome of… 
2010
2010
Abstract 3578: New Angiochem-modified doxorubicin with increased brain penetration and efficacy against brain tumors
The blood-brain barrier (BBB) is mainly formed by brain capillary endothelial cells which are closely sealed by tight junctions… 
2008
2008
ANG1005: PRELIMINARY CLINICAL SAFETY AND TOLERABILITY IN PATIENTS WITH RECURRENT MALIGNANT GLIOMA
Background: The blood–brain barrier (BBB) complicates the clinical treatment of most CNS diseases, including malignant glioma (MG… 
2008
2008
ET-09 : A new drug, ANG1005, a conjugate of Paclitaxel and Angiopep peptide vector able to cross the Blood-Brain Barrier for the treatment of brain cancers.
The blood-brain barrier (BBB) is mainly formed by brain capillary endothelial cells which are closely sealed by tight junctions… 
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