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Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations.
TLDR
DW-MRI should be tested as an imaging biomarker in the context of well-defined clinical trials, by adding DW-MRI to existing NCI-sponsored trials, particularly those with tissue sampling or survival indicators, and standards for measurement, analysis, and display are needed.
Comparison of MR/ultrasound fusion-guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer.
TLDR
Among men undergoing biopsy for suspected prostate cancer, targeted MR/ultrasound fusionBiopsy, compared with standard extended-sextant ultrasound-guided biopsy, was associated with increased detection of high-risk prostate cancer and decreased detection of low- risk prostate cancer.
ESUR prostate MR guidelines 2012
TLDR
Clinical indications, and minimal and optimal imaging acquisition protocols are provided, and a structured reporting system (PI-RADS) is described.
Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America.
TLDR
The present study shows that mutations in FH are associated with HLRCC in North America, and expands the histologic spectrum of renal tumors and FH mutations associated withHLRCC.
Imaging of angiogenesis: from microscope to clinic
TLDR
The importance of angiogenesis in cancer, chronic inflammatory diseases, age-related macular degeneration and reversal of ischemic heart and limb disease provides incentive for meeting these challenges.
Imaging prostate cancer: a multidisciplinary perspective.
TLDR
A multidisciplinary perspective on the optimal role of modern imaging in prostate cancer detection, staging, treatment planning, and follow-up is presented.
BHD mutations, clinical and molecular genetic investigations of Birt–Hogg–Dubé syndrome: a new series of 50 families and a review of published reports
TLDR
BHDS is characterised by a spectrum of mutations, and clinical heterogeneity both among and within families, and the first germline missense mutation in BHD c.1978A>G (K508R) is reported.
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