ALK gene

Known as: Anaplastic Lymphoma Kinase (Ki-1) Gene, ANAPLASTIC LYMPHOMA KINASE, ALK/NPM1 FUSION GENE 
This gene is involved in brain development and neuronal specificity.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Genomic analysis has greatly influenced the diagnosis and clinical management of patients affected by diverse forms of… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND ALK fusion genes occur in a subset of non-small-cell lung cancers (NSCLCs). We assessed the tolerability and activity… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND ALK gene rearrangement defines a new molecular subtype of non-small-cell lung cancer (NSCLC). In a recent phase 1… (More)
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Highly Cited
2010
Highly Cited
2010
The EML4 (echinoderm microtubule-associated protein-like 4)-ALK (anaplastic lymphoma kinase) fusion-type tyrosine kinase is an… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE The EML4-ALK fusion oncogene represents a novel molecular target in a small subset of non-small-cell lung cancers (NSCLC… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene resulting from… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE EML4-ALK is a transforming fusion tyrosine kinase, several isoforms of which have been identified in lung cancer… (More)
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Highly Cited
2008
Highly Cited
2008
Neuroblastoma, an embryonal tumour of the peripheral sympathetic nervous system, accounts for approximately 15% of all deaths due… (More)
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Highly Cited
2007
Highly Cited
2007
Improvement in the clinical outcome of lung cancer is likely to be achieved by identification of the molecular events that… (More)
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Highly Cited
2000
Highly Cited
2000
Inflammatory myofibroblastic tumors (IMTs) are neoplastic mesenchymal proliferations featuring an inflammatory infiltrate… (More)
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