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ALK gene
Known as:
Anaplastic Lymphoma Kinase (Ki-1) Gene
, ANAPLASTIC LYMPHOMA KINASE
, ALK/NPM1 FUSION GENE
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This gene is involved in brain development and neuronal specificity.
National Institutes of Health
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Related topics
Related topics
47 relations
ALK protein, human
Abdominal Inflammatory Myofibroblastic Tumor
Adenocarcinoma of lung (disorder)
Anaplastic Large Cell Lymphoma, ALK-Positive
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Narrower (1)
ALK wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Abstract 2136: Entrectinib is effective against the gatekeeper and other emerging resistance mutations in NTRK-, ROS1- and ALK- rearranged cancers
G. Wei
,
E. Ardini
,
+10 authors
Gary Li
2016
Corpus ID: 88750107
Gene rearrangements involving NTRK1, NTRK2, NTRK3, ROS1 and ALK result in oncogenic fusion proteins that have been identified in…
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2015
2015
Identi fi cation of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB 4 transcripts
Irene Scarfò
,
E. Pellegrino
,
+22 authors
R. Piva
2015
Corpus ID: 39738077
Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts Irene Scarfò,* Elisa…
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Review
2015
Review
2015
[Molecular mechanisms of targeted drug resistance in lung cancer and its therapeutic strategy].
S. Yano
Nihon rinsho. Japanese journal of clinical…
2015
Corpus ID: 37214591
Several driver oncogenes, including EGFR mutations and ALK rearrangement, have been identified in lung cancer. The EGFR tyrosine…
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2015
2015
[Expression of microRNA in ALK-negative anaplastic large cell lymphoma and CD30-positive peripheral T cell lymphoma, not otherwise specified].
Chen Wang
,
Xiaoyan Chen
,
Xin Chen
,
Yihui He
,
Li-Yu Cao
Zhonghua bing li xue za zhi = Chinese journal of…
2015
Corpus ID: 45769136
OBJECTIVE To study the role of microRNAs (miRNAs) in ALK-negative anaplastic large cell lymphoma and CD30 positive peripheral T…
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2015
2015
Using the Second-Generation ALK Inhibitor AP 26113 in Human NPM-ALK – Positive Anaplastic Large Cell Lymphoma
M. Ceccon
,
L. Mologni
,
+4 authors
C. Gambacorti-Passerini
2015
Corpus ID: 21877166
ALK is a tyrosine kinase receptor involved in a broad range of solid and hematologic tumors. Among 70% to 80% of ALKþ anaplastic…
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2010
2010
Frequencies of ALK and ROS in NSCLC FFPE tumor samples utilizing a highly specific immunohistochemistry-based assay and FISH analysis.
V. Rimkunas
,
K. Crosby
,
+6 authors
H. Haack
2010
Corpus ID: 83765782
10536 Background: Receptor tyrosine kinases ALK and ROS are expressed as oncogenic fusion proteins in approximately 2%-5% of all…
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2010
2010
A Japanese nationwide network for the diagnosis of EML4-ALK-positive lung cancer: A joint study of ALCAS and NEJ004.
M. Soda
,
A. Inoue
,
+7 authors
H. Mano
2010
Corpus ID: 74615260
10534 Background: EML4-ALK is a fusion-type tyrosine kinase with a marked transforming ability both in vitro and in vivo, and may…
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1999
1999
NPM/ALK rearrangements in indolent cutaneous lesions
F. Hernández
,
O. López
,
+4 authors
Josep F. Nomdedeu
Leukemia
1999
Corpus ID: 6855191
The (2;5)(p23;q35) translocation, which results in the fusion of the NPM (nucleophosmin) gene on chromosome 5q35 with the novel…
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1998
1998
NUCLEOPHOSMIN (NPM)/ANAPLASTIC LYMPHOMA KINASE (ALK) FUSION TRANSCRIPT IN MALIGNANT LYMPHOMA
Y. Kaneita
,
T. Uchida
,
U. Sawada
,
T. Horie
1998
Corpus ID: 88551851
Highly Cited
1974
Highly Cited
1974
Covalent structure of calf-thymus ALK-histone.
Pierre Sautielère
,
Danièle Tyrou
,
B. Laine
,
J. Mizon
,
Pierre Ruffin
,
Gérard Biserte
European Journal of Biochemistry
1974
Corpus ID: 26631219
Highly purified calf thymus ALK-histone (histone rich in alanine, lecine and lysine) was isolated from F2a2 histone fraction by…
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