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ALK wt Allele

Known as: ALK, Anaplastic Lymphoma Kinase (Ki-1) wt Allele 
Human ALK wild-type allele is located within 2p23 and is approximately 729 kb in length. This allele, which encodes ALK tyrosine kinase receptor… 
National Institutes of Health

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12 relations
2p23ALK protein, humanAdenocarcinoma of lung (disorder)Anaplastic Large Cell Lymphoma, ALK-Positive

Broader (1)

ALK gene

Papers overview

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2016
2016
Spitz Tumors
Spitz tumors are a group of melanocytic neoplasms with distinct morphological features that tend to affect young individuals… 
2015
2015
ALK-FISH borderline cases in non-small cell lung cancer: Implications for diagnostics and clinical decision making.
2012
2012
Incidence and patterns of ALK FISH abnormalities seen in a large unselected series of lung carcinomas
BackgroundAnaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements have been reported in 2-13% of patients with non… 
2010
2010
Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemia.
NPM-ALK (nucleophosmin-anaplastic lymphoma kinase) and TPM3-ALK (nonmuscular tropomyosin 3-anaplastic lymphoma kinase) are… 
2010
2010
Phase I study of PF-03446962, a fully human mAb against ALK 1, a TGFβ receptor involved in tumor angiogenesis.
3009 Background: Transforming growth factor β (TGF β) is a cytokine able to regulate many biological processes in cancer. At… 
2010
2010
Linkage of expression of chemokine receptors (CXCR3 and CCR4) and cytotoxic molecules in peripheral T cell lymphoma, not otherwise specified and ALK-negative anaplastic large cell lymphoma
Peripheral T cell lymphoma not otherwise specified (PTCL-N) and ALK-negative anaplastic large cell lymphoma (ALCL) are… 
2007
2007
Identification of BMP 9 and BMP 10 as functional activators of the orphan activin receptor-like kinase 1 ( ALK 1 ) in endothelial cells
1Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe Mixte INSERM (EMI 01-05), Grenoble, France… 
2002
2002
Epstein-Barr virus association and ALK gene expression in anaplastic large-cell lymphoma.
Anaplastic large cell lymphoma of T/null-cell type (ALCL) is associated with a characteristic genetic abnormality t(2;5) that… 
Highly Cited
1998
Highly Cited
1998
Detection of the t(2;5)‐associated NPM/ALK fusion cDNA in peripheral blood cells of healthy individuals
The translocation t(2;5), which leads to the fusion of the nucleophosmin gene (NPM) on chromosome 5q35 to the receptor kinase ALK… 
1998
1998
Reproducibility of skin prick test results in epidemiologic studies: a comparison of two devices
The reproducibility of skin prick tests under field conditions is essential for comparing prevalences between centers in… 
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