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AICDA gene

Known as: AID, CDA2, Activation-Induced Cytidine Deaminase Gene 
This gene plays a role in both class-switch recombination in B-lymphocytes and cytidine deamination.
National Institutes of Health

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AICDA wt Allele
Activation-Induced Cytidine DeaminaseDNA Methylation RegulationHydrolysisb cell differentiation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Genomic Profile and Pathologic Features of Diffuse Large B-Cell Lymphoma Subtype of Methotrexate-associated Lymphoproliferative Disorder in Rheumatoid Arthritis Patients
Rheumatoid arthritis patients often develop the diffuse large B-cell lymphoma subtype of methotrexate-associated… 
Review
2015
Review
2015
Antibody Affinity Maturation in Fishes—Our Current Understanding
It has long been believed that fish lack antibody affinity maturation, in part because they were thought to lack germinal centers… 
2015
2015
Novel and recurrent AID mutations underlie prevalent autosomal recessive form of HIGM in consanguineous patients
Immunoglobulin class switch recombination deficiencies (Ig-CSR-D) are characterized by normal or elevated serum IgM level and… 
2011
2011
Comparison of two POLQ mutants reveals that a polymerase‐inactive POLQ retains significant function in tolerance to etoposide and γ‐irradiation in mouse B cells
DNA polymerase θ (POLQ) is a family A polymerase that contains an intrinsic helicase domain. POLQ has been implicated in… 
Highly Cited
2008
Highly Cited
2008
Genetic or pharmaceutical blockade of p110delta phosphoinositide 3-kinase enhances IgE production.
2008
2008
Induction of A:T Mutations Is Dependent on Cellular Environment but Independent of Mutation Frequency and Target Gene Location
Based on its substrate specificity, activation-induced cytidine deaminase can directly induce C:G mutations in Ig genes. However… 
2006
2006
The cytidine deaminase AID exhibits similar functional properties in yeast and mammals.
Review
2001
Review
2001
The hyper IgM syndrome
The hyper IgM syndrome is a rare, inherited immune deficiency disorder resulting from defects in the CD40 ligand/ CD40-signaling… 
1989
1989
Fluid flow measurement
1975
1975
Cytidine deaminase: a new genetic polymorphism demonstrated in human granulocytes.
Cytidine deaminase in human white blood cells has three electrophoretic phenotypes representing the homozygous and heterozygous… 
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