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AICDA gene

Known as: AID, CDA2, Activation-Induced Cytidine Deaminase Gene 
This gene plays a role in both class-switch recombination in B-lymphocytes and cytidine deamination.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
  • M. Greaves
  • Nature Reviews. Cancer
  • 2018
  • Corpus ID: 29153578
In this Review, I present evidence supporting a multifactorial causation of childhood acute lymphoblastic leukaemia (ALL), a… 
Highly Cited
2017
Highly Cited
2017
We applied a fusion of CRISPR-Cas9 and activation-induced cytidine deaminase (Target-AID) for point mutagenesis at genomic… 
Highly Cited
2011
Highly Cited
2011
To elucidate the specific role of somatic hypermutation (SHM) in mucosal immunity, we generated mice carrying a knock-in point… 
Highly Cited
2011
Highly Cited
2011
The cytidine deaminase AID hypermutates immunoglobulin genes but can also target oncogenes, leading to tumorigenesis. The extent… 
Highly Cited
2009
Highly Cited
2009
Jawless vertebrates use variable lymphocyte receptors (VLR) comprised of leucine-rich-repeat (LRR) segments as counterparts of… 
Review
2008
Review
2008
Antibody class switching occurs in mature B cells in response to antigen stimulation and costimulatory signals. It occurs by a… 
Highly Cited
2008
Highly Cited
2008
The transcription factors Foxo1, Foxo3 and Foxo4 modulate cell fate 'decisions' in diverse systems. Here we show that Foxo1… 
Highly Cited
2005
Highly Cited
2005
IL-21 is a type I cytokine that influences the function of T cells, NK cells, and B cells. In this study, we report that IL-21… 
Highly Cited
2004
Highly Cited
2004
A feature of Ig hypermutation is the presence of hypermutable DNA sequences that are preferentially found in the V regions of Ig…