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The prerequisite to prevent childhood B-cell acute lymphoblastic leukemia (B-ALL) is to decipher its etiology. The current model… Expand In favor of their outgrowth, cancer cells must resist immune surveillance and edit the immune response. Cancer immunoediting is… Expand BACKGROUND
Mobile health Applications (mHealth Apps) are opening the way to patients' responsible and active involvement with… Expand The activation-induced cytidine deaminase (AID; also known as AICDA) enzyme is required for somatic hypermutation and class… Expand The Ranunculus auricomus complex is an interesting model system for studying the evolution and diversity of apomictic polyploid… Expand Most human B cell non-Hodgkin's lymphomas (B-NHLs) derive from germinal centers (GCs), the structure in which B cells undergo… Expand APOBEC3G (apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G) was identified as an anti-HIV-1 (human… Expand Immunoglobulin (Ig) heavy and light chain loci undergo V, (D) and J gene recombination in bone marrow, giving rise to the diverse… Expand A recent work published in Molecular Immunology examined the editing activity of activation-induced deaminase (AID) in yeast… Expand In mice, activation induced deaminase, AID, is expressed only in germinal center B cells. It is required for the initiation of… Expand