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Autonomous video surveillance and monitoring of human subjects in video has a rich history. Many deployed systems are able to reliably track human motion in indoor and controlled outdoor environments , e.g. parking lots and university campuses. A challenging domain of vital military importance is the surveillance of non-cooperative and camouflaged targets(More)
In extremely acidic environments, enteric bacteria such as Escherichia coli rely on the amino acid antiporter AdiC to expel protons by exchanging intracellular agmatine (Agm(2+)) for extracellular arginine (Arg(+)). AdiC is a representative member of the amino acid-polyamine-organocation (APC) superfamily of membrane transporters. The structure of(More)
For a better evaluation of the accuracy of VIs in estimating biophysical parameters, a "true" VI value attributed only to the vegetation signal andfree of any contamination is needed. In this article, pure vegetation spectra were extractedfrom a set of open and closed canopies by unmix-ing the green vegetation signalfrom the background component. Canopy(More)
Serotonin or 5-hydroxytryptamine (5-HT) regulates a wide spectrum of human physiology through the 5-HT receptor family. We report the crystal structures of the human 5-HT1B G protein-coupled receptor bound to the agonist antimigraine medications ergotamine and dihydroergotamine. The structures reveal similar binding modes for these ligands, which occupy the(More)
Cancer cells consume large quantities of glucose and primarily use glycolysis for ATP production, even in the presence of adequate oxygen. This metabolic signature (aerobic glycolysis or the Warburg effect) enables cancer cells to direct glucose to biosynthesis, supporting their rapid growth and proliferation. However, both causes of the Warburg effect and(More)
Virulent enteric pathogens such as Escherichia coli strain O157:H7 rely on acid-resistance (AR) systems to survive the acidic environment in the stomach. A major component of AR is an arginine-dependent arginine:agmatine antiporter that expels intracellular protons. Here, we report the crystal structure of AdiC, the arginine:agmatine antiporter from E. coli(More)
Liver natural killer (NK) cells were recently reported to possess memory-like properties in contact hypersensitivity (CHS) models. However, the phenotype and origin of these "memory" NK cells cannot be distinguished from other NK cell subpopulations. Here, we define the transcriptional, phenotypic, and functional features of liver NK cell subsets and their(More)
Background modeling is a common component in video surveillance systems and is used to quickly identify regions of interest. To increase the robustness of background subtraction techniques, researchers have developed techniques to update the background model and also developed proba-bilistic/statistical approaches for thresholding the difference. This paper(More)