FAQ

Activation-Induced Cytidine Deaminase

Known as: Cytidine Aminohydrolase, EC 3.5.4.5 
Activation-induced cytidine deaminase (198 aa, ~24 kDa) is encoded by the human AICDA gene. This protein plays a role in both B-cell functioning and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
024619922017

Related topics

Related topics

7 relations
AICDA geneEnzyme GeneHydrolase GeneHydrolysis
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Activation-Induced Cytidine Deaminase
Lymph Node Tissue
Tonsillar Tissue
b cell differentiation
Enzyme Gene
Hydrolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Epigenetic targeting of activation-induced cytidine deaminase.
Activation-induced cytidine deaminase (AID) initiates class switch recombination (CSR) and somatic hypermutation (SHM) by… (More)
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2013
2013
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase.
Activation-induced cytidine deaminase (AID) is essential for the somatic hypermutation (SHM) and class-switch recombination (CSR… (More)
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2010
2010
Widespread genomic breaks from activation-induced cytidine deaminase are prevented by homologous recombination
Activation-induced cytidine deaminase (AID) is required for somatic hypermutation and immunoglobulin class switching in activated… (More)
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2008
2008
Evolution of phosphorylation-dependent regulation of activation-induced cytidine deaminase.
Interaction of activation-induced cytidine deaminase (AID) with replication protein A (RPA) has been proposed to promote AID… (More)
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Highly Cited
2007
Highly Cited
2007
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signaling
Activation-induced cytidine deaminase (AID) is involved in somatic DNA alterations of the immunoglobulin gene for amplification… (More)
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Highly Cited
2007
Highly Cited
2007
Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.
Activation-induced cytidine deaminase (AID) plays a role as a genome mutator in activated B cells, and inappropriate expression… (More)
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Highly Cited
2006
Highly Cited
2006
Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation.
Activation-induced cytidine deaminase (AID) initiates Ig class switch recombination and somatic hypermutation by producing U:G… (More)
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2006
2006
The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination.
Activation-induced cytidine deaminase (AID) is a single-stranded DNA deaminase required for somatic hypermutation of… (More)
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2005
2005
The double-edged sword of activation-induced cytidine deaminase.
Activation-induced cytidine deaminase (AID) is required for Ig class switch recombination, a process that introduces DNA double… (More)
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Highly Cited
2004
Highly Cited
2004
Biochemical analysis of hypermutational targeting by wild type and mutant activation-induced cytidine deaminase.
The synthesis of high affinity antibodies requires activation-induced cytidine deaminase (AID) to initiate somatic hypermutation… (More)
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