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Activation-Induced Cytidine Deaminase
Known as:
Cytidine Aminohydrolase
, EC 3.5.4.5
Activation-induced cytidine deaminase (198 aa, ~24 kDa) is encoded by the human AICDA gene. This protein plays a role in both B-cell functioning and…
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National Institutes of Health
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Related topics
Related topics
7 relations
AICDA gene
DNA Methylation Regulation
Enzyme Gene
Hydrolysis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The cell cycle restricts activation-induced cytidine deaminase activity to early G1
Qiao Wang
,
Kyong-Rim Kieffer-Kwon
,
+9 authors
D. Robbiani
The Journal of experimental medicine
2017
Corpus ID: 8253674
Activation-induced cytidine deaminase (AID) converts cytosine into uracil to initiate somatic hypermutation (SHM) and class…
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Review
2011
Review
2011
Complex regulation and function of activation-induced cytidine deaminase.
J. Stavnezer
Trends in immunology
2011
Corpus ID: 32527922
Review
2009
Review
2009
Biochemical Basis of Immunological and Retroviral Responses to DNA-targeted Cytosine Deamination by Activation-induced Cytidine Deaminase and APOBEC3G*
L. Chelico
,
P. Pham
,
J. Petruska
,
M. Goodman
The Journal of Biological Chemistry
2009
Corpus ID: 1193259
Activation-induced cytidine deaminase (AID) and APOBEC3G catalyze deamination of cytosine to uracil on single-stranded DNA…
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2008
2008
Impact of Phosphorylation and Phosphorylation-null Mutants on the Activity and Deamination Specificity of Activation-induced Cytidine Deaminase*
P. Pham
,
M. Smolka
,
+4 authors
M. Goodman
Journal of Biological Chemistry
2008
Corpus ID: 22750381
Activation-induced cytidine deaminase (AID) initiates somatic hypermutation and class switch recombination in B cells by…
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Highly Cited
2007
Highly Cited
2007
Expression of activation‐induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis
Tadayuki Kou
,
H. Marusawa
,
+7 authors
T. Chiba
International journal of cancer
2007
Corpus ID: 41677213
Activation‐induced cytidine deaminase (AID) plays a role as a genome mutator in activated B cells, and inappropriate expression…
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Highly Cited
2006
Highly Cited
2006
The Transcription Elongation Complex Directs Activation-Induced Cytidine Deaminase-Mediated DNA Deamination
E. Besmer
,
E. Market
,
F. Papavasiliou
Molecular and Cellular Biology
2006
Corpus ID: 38174
ABSTRACT Activation-induced cytidine deaminase (AID) is a single-stranded DNA deaminase required for somatic hypermutation of…
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2006
2006
Identification of a Specific Domain Required for Dimerization of Activation-induced Cytidine Deaminase*
Jishu Wang
,
R. Shinkura
,
M. Muramatsu
,
H. Nagaoka
,
K. Kinoshita
,
T. Honjo
Journal of Biological Chemistry
2006
Corpus ID: 8671810
Activation-induced cytidine deaminase (AID) is essential to all three genetic alterations required for generation of antigen…
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Highly Cited
2004
Highly Cited
2004
Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency.
P. Quartier
,
J. Bustamante
,
+17 authors
A. Durandy
Clinical immunology
2004
Corpus ID: 23424557
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