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AF64A

Known as: AF64A-picrylsulfonate 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

ethylcholine aziridinium

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction
Highly Cited
2010
Highly Cited
2010
Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease.
Highly Cited
2010
Highly Cited
2010
Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model.
Review
2004
Review
2004
(-)-Deprenyl, a selective MAO-B inhibitor, with apoptotic and anti-apoptotic properties.
Highly Cited
1998
Highly Cited
1998
Comparative Studies of Huperzine A, E2020, and Tacrine on Behavior and Cholinesterase Activities
Review
1988
Review
1988
Animal models of Alzheimer's disease: experimental cholinergic denervation
Review
1986
Review
1986
Potential animal models for senile dementia of Alzheimer's type, with emphasis on AF64A-induced cholinotoxicity.
  • A. Fisher, I. Hanin
  • Annual review of pharmacology and toxicology
  • 1986
  • Corpus ID: 23593146
In this review we have described and critiqued several commonly used proposed animal models for SDAT. In particular, we have… 
Highly Cited
1983
Highly Cited
1983
Selective Presynaptic Cholinergic Neurotoxicity Following Intrahippocampal AF64A Injection in Rats
Abstract: Compound AF64A, ethylcholine mustard aziridinium ion (0.4–8 nmol) was stereotaxically administered into rat dorsal… 
Highly Cited
1982
Highly Cited
1982
Long-term central cholinergic hypofunction induced in mice by ethylcholine aziridinium ion (AF64A) in vivo.
Ethylcholine mustard aziridinium ion (AF64A), a neurotoxic choline analog, was evaluated for its interactions with the… 
Highly Cited
1981
Highly Cited
1981
The AF64a-treated mouse: possible model for central cholinergic hypofunction.
A loss in the number of functional, sodium ion-dependent, high-affinity choline transport sites was observed in the cortex and… 
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