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ethylcholine aziridinium

Known as: 1-ethyl-1-(2-hydroxyethyl)aziridinium chloride, ethylcholine aziridinium chloride, ethylcholine mustard aziridinium 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
In this critical review, the ring opening of non-activated 2-substituted aziridines via intermediate aziridinium salts will be… Expand
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Highly Cited
2007
Highly Cited
2007
The development of biotech drugs such as peptides and proteins that act in the central nervous system has been significantly… Expand
Highly Cited
2000
Highly Cited
2000
Activity-dependent neurotrophic factor (ADNF) is a glia-derived protein that is neuroprotective at femtomolar concentrations. A… Expand
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2000
2000
The involvement of nitric oxide in neurodegenerative processes still remains incompletely characterized. Although nitric oxide… Expand
Highly Cited
1996
Highly Cited
1996
Neurodegenerative diseases, in which neuronal cell disintegrate, bring about deteriorations in cognitive functions as is… Expand
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Highly Cited
1987
Highly Cited
1987
The time course of the cholinotoxicity of ethylcholine aziridinium ion (AF64A) has been investigated. Rats were injected with… Expand
Highly Cited
1987
Highly Cited
1987
The present study examined the nature of the cognitive deficits associated with a selective decrease of cholinergic activity in… Expand
Highly Cited
1984
Highly Cited
1984
Ethylcholine aziridinium ion solution (AF64A), a putative specific cholinergic neurotoxin, was injected bilaterally into the… Expand
Review
1984
Review
1984
AF64A is a toxin which can diminish irreversibly cholinergic transmission in vivo (1, 2). Disruption of neurotransmitter function… Expand
Highly Cited
1982
Highly Cited
1982
Ethylcholine mustard aziridinium ion (AF64A), a neurotoxic choline analog, was evaluated for its interactions with the… Expand