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AF 353

Known as: AF-353, AF353 cpd 
 
National Institutes of Health

Papers overview

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2019
2019
To evaluate the role that intravesical P2X2/3 purinergic receptors (P2X2/3Rs) play in early and advanced neurogenic lower urinary… Expand
2018
2018
  • J. Wang, Yao Wang, +11 authors Y. Yu
  • Proceedings of the National Academy of Sciences
  • 2018
  • Corpus ID: 4981140
Significance Allosteric regulation, produced by the binding of a ligand at an allosteric site topographically distinct from the… Expand
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2016
2016
The late asthmatic response (LAR) is a defining symptom of asthma and is regularly used as a model for proof of concept clinical… Expand
Highly Cited
2015
Highly Cited
2015
Acute inhibition of purinergic receptors with a selective P2X3 antagonist prevents transmission of information from taste buds to… Expand
2015
2015
Activation of TRPV4 causes vagal nerve depolarisation, single airway fibre firing and reflex cough in the guinea pig (GP) through… Expand
2012
2012
•  Activation of bronchopulmonary C‐fibres can lead to parasympathetic reflex bronchoconstriction, mucus secretion, as well as… Expand
2012
2012
What's known on the subject? and What does the study add? 
Highly Cited
2010
Highly Cited
2010
Background and purpose:  Purinoceptors containing the P2X3 subunit (P2X3 homotrimeric and P2X2/3 heterotrimeric) are members of… Expand
Highly Cited
2010
Highly Cited
2010
Pain remains an area of considerable unmet clinical need, and this is particularly true of pain associated with bone metastases… Expand
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2010
2010
Pain remains an area of considerable unmet clinical need, and this is particularly true of pain associated with bone metastases… Expand
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