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AF 353

Known as: AF-353, AF353 cpd 
 
National Institutes of Health

Papers overview

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2019
2019
OBJECTIVES To evaluate the role that intravesical P2X2/3 purinergic receptors (P2X2/3Rs) play in early and advanced neurogenic… Expand
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2018
2018
  • Jin Wang, Yao Wang, +11 authors Ye Yu
  • Proceedings of the National Academy of Sciences
  • 2018
  • Corpus ID: 4981140
Significance Allosteric regulation, produced by the binding of a ligand at an allosteric site topographically distinct from the… Expand
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2016
2016
The late asthmatic response (LAR) is a defining symptom of asthma and is regularly used as a model for proof of concept clinical… Expand
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2015
2015
Taste buds release ATP to activate ionotropic purinoceptors composed of P2X2 and P2X3 subunits, present on the taste nerves. Mice… Expand
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2015
2015
Activation of TRPV4 causes vagal nerve depolarisation, single airway fibre firing and reflex cough in the guinea pig (GP) through… Expand
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2012
2012
Activation of vagal afferent sensory C-fibres in the lungs leads to reflex responses that produce many of the symptoms associated… Expand
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2012
2012
OBJECTIVE To evaluate the role of bladder sensory purinergic P2X3 and P2X2/3 receptors on modulating the activity of lumbosacral… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND AND PURPOSE Purinoceptors containing the P2X3 subunit (P2X3 homotrimeric and P2X2/3 heterotrimeric) are members of the… Expand
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Highly Cited
2010
Highly Cited
2010
Pain remains an area of considerable unmet clinical need, and this is particularly true of pain associated with bone metastases… Expand
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2010
2010
Pain remains an area of considerable unmet clinical need, and this is particularly true of pain associated with bone metastases… Expand
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