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AF 353
Known as:
AF-353
, AF353 cpd
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Electroacupuncture Alleviates Bladder Overactivity via Inhabiting Bladder P2X3 Receptor
Qi-fan Feng
,
An-dong Zhang
,
Man Xing
,
Xi Wang
,
Shu-Ren Ming
,
Yue-Lai Chen
Evidence-Based Complementary and Alternative…
2020
Corpus ID: 214588351
Electroacupuncture (EA) has been widely applied for overactive bladder, but the mechanism of its action remains to be clarified…
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Highly Cited
2018
Highly Cited
2018
Druggable negative allosteric site of P2X3 receptors
Jin Wang
,
Yao Wang
,
+11 authors
Ye Yu
Proceedings of the National Academy of Sciences
2018
Corpus ID: 4981140
Significance Allosteric regulation, produced by the binding of a ligand at an allosteric site topographically distinct from the…
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2018
2018
Modulatory effects of intravesical P2X2/3 purinergic receptor inhibition on lower urinary tract electromyographic properties and voiding function of female rats with moderate or severe spinal cord…
B. Salazar
,
K. Hoffman
,
+4 authors
A. Munoz
BJU International
2018
Corpus ID: 52821365
To evaluate the role that intravesical P2X2/3 purinergic receptors (P2X2/3Rs) play in early and advanced neurogenic lower urinary…
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Highly Cited
2015
Highly Cited
2015
Postsynaptic P2X3‐containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice
A. Vandenbeuch
,
E. Larson
,
+4 authors
S. Kinnamon
Journal of Physiology
2015
Corpus ID: 23299228
Acute inhibition of purinergic receptors with a selective P2X3 antagonist prevents transmission of information from taste buds to…
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2014
2014
MP17-13 FUNCTIONAL-MRI DURING BLADDER CYSTOMETRY IN SPINAL CORD-INJURED AND INTACT FEMALE RATS
Kelvin K. Wong
,
T. Boone
,
A. Munoz
2014
Corpus ID: 71553115
2012
2012
A role for ATP in bronchoconstriction‐induced activation of guinea pig vagal intrapulmonary C‐fibres
Letitia A. Weigand
,
A. Ford
,
B. Undem
Journal of Physiology
2012
Corpus ID: 206381361
• Activation of bronchopulmonary C‐fibres can lead to parasympathetic reflex bronchoconstriction, mucus secretion, as well as…
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2012
2012
Modulation of bladder afferent signals in normal and spinal cord‐injured rats by purinergic P2X3 and P2X2/3 receptors
A. Munoz
,
G. Somogyi
,
T. Boone
,
A. Ford
,
Christopher P. Smith
BJU International
2012
Corpus ID: 8215908
What's known on the subject? and What does the study add?
Highly Cited
2010
Highly Cited
2010
AF‐353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist
J. Gever
,
R. Soto
,
+9 authors
A.P.D.W. Ford
British Journal of Pharmacology
2010
Corpus ID: 13924743
Background and purpose: Purinoceptors containing the P2X3 subunit (P2X3 homotrimeric and P2X2/3 heterotrimeric) are members of…
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Highly Cited
2010
Highly Cited
2010
Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats.
T. K. Y. Kaan
,
P. Yip
,
+9 authors
S. McMahon
Brain : a journal of neurology
2010
Corpus ID: 3916478
Pain remains an area of considerable unmet clinical need, and this is particularly true of pain associated with bone metastases…
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2010
2010
Systemic blockade of P 2 X 3 and P 2 X 2 / 3 receptors attenuates bone cancer pain behaviour in rats
T. K. Y. Kaan
,
P. Yip
,
+9 authors
S. McMahon
2010
Corpus ID: 4822731
Pain remains an area of considerable unmet clinical need, and this is particularly true of pain associated with bone metastases…
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