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ADRA1B gene

Known as: ALPHA-1B-ADRENERGIC RECEPTOR, adrenoceptor alpha 1B, ADRA1B 
This gene is involved in the induction of neoplastic transformation and receptor signaling.
National Institutes of Health

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ADRA1B wt Allele
ADRA1D geneAlpha-1B Adrenergic Receptor, humanCell ProliferationG Protein-Coupled Receptor Signaling
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Papers overview

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2016
2016
From Bench to Bedside: Attempt to Evaluate Repositioning of Drugs in the Treatment of Metastatic Small Cell Lung Cancer (SCLC)
BACKGROUNDS Based on in vitro data and results of a recent drug repositioning study, some medications approved by the FDA for the… Expand
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2015
2015
Endogenous microRNAs in human microvascular endothelial cells regulate mRNAs encoded by hypertension-related genes.
The goal of this study was to systematically identify endogenous microRNAs (miRNAs) in endothelial cells that regulate mRNAs… Expand
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2014
2014
Effects of colostrum versus formula feeding on hepatic glucocorticoid and α₁- and β₂-adrenergic receptors in neonatal calves and their effect on glucose and lipid metabolism.
Neonatal energy metabolism in calves has to adapt to extrauterine life and depends on colostrum feeding. The adrenergic and… Expand
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2014
2014
Aberrant α-Adrenergic Hypertrophic Response in Cardiomyocytes from Human Induced Pluripotent Cells
Summary Cardiomyocytes from human embryonic stem cells (hESC-CMs) and induced pluripotent stem cells (hiPSC-CMs) represent new… Expand
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2012
2012
A high density linkage disequilibrium mapping in 14 noradrenergic genes: evidence of association between SLC6A2, ADRA1B and ADHD
Pharmacological evidence suggests the importance of noradrenergic and other monoaminergic neurotransmitters in the aetiology and… Expand
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2011
2011
Epistasis between neurochemical gene polymorphisms and risk for ADHD
A number of genes with function related to synaptic neurochemistry have been genetically associated with attention deficit… Expand
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Highly Cited
2010
Highly Cited
2010
A genome-wide association study on African-ancestry populations for asthma.
BACKGROUND Asthma is a complex disease characterized by striking ethnic disparities not explained entirely by environmental… Expand
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2010
2010
The effects of sex and method of blood pressure measurement on genetic associations with blood pressure in the PAMELA study.
BACKGROUND Phenotypic accuracy and specificity are essential for a successful genetic association study. Blood pressure (BP… Expand
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2010
2010
Domperidone Treatment for Gastroparesis: Demographic and Pharmacogenetic Characterization of Clinical Efficacy and Side-Effects
BackgroundDomperidone is a useful alternative to metoclopramide for treatment of gastroparesis due to better tolerability… Expand
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2004
2004
The thiazide-sensitive Na(+)-Cl(-) cotransporter gene, C1784T, and adrenergic receptor-beta3 gene, T727C, may be gene polymorphisms susceptible to the antihypertensive effect of thiazide diuretics.
The response of blood pressure to thiazide diuretics (TZDs) differs among individuals. The prediction of the antihypertensive… Expand
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