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ADORA3 wt Allele
Known as:
RP11-552M11.7
, UNQ1931/PRO4406
, Adenosine A3 Receptor wt Allele
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Human ADORA3 wild-type allele is located in the vicinity of 1p13.2 and is approximately 81 kb in length. This allele, which encodes adenosine A3…
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National Institutes of Health
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Related topics
Related topics
7 relations
1p21-p13
Adenosine A3 Receptor
G Protein-Coupled Receptor Signaling
Ligand Binding
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Broader (1)
ADORA3 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
A phase II, randomized, double-blind, placebo-controlled trial evaluating efficacy and safety of namodenoson (CF102), an A3 adenosine receptor agonist (A3AR), as a second-line treatment in patients…
S. Stemmer
,
N. Manojlovic
,
+17 authors
J. Llovet
Journal of Clinical Oncology
2019
Corpus ID: 262113593
2503 Background: There is no established primary treatment for patients with advanced HCC and severe liver dysfunction (Child…
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2018
2018
The Adenosine-Receptor Axis in Chronic Pain
D. Salvemini
,
T. Doyle
,
T. Largent-Milnes
,
T. Vanderah
2018
Corpus ID: 57393534
Chronic pain is a widespread problem that plagues an estimated 10 to 30% of the world’s population. The current therapeutic…
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2017
2017
Species differences and mechanism of action of A3 adenosine receptor allosteric modulators
Lili Du
,
Zhang-Guo Gao
,
+7 authors
J. Auchampach
Purinergic Signalling Purinergic Signalling
2017
Corpus ID: 255135759
Activity of the A3 adenosine receptor (AR) allosteric modulators LUF6000 (2-cyclohexyl-N-(3,4-dichlorophenyl)-1H-imidazo [4,5-c…
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2016
2016
Supplemental Data Peripheral Adenosine A 3 Receptor Activation Causes Regulated Hypothermia in Mice that is Dependent on Central Histamine H 1 Receptors
J. Carlin
,
D. Tosh
,
+6 authors
M. Reitman
2016
Corpus ID: 43099919
Adenosine can induce hypothermia, as previously demonstrated for adenosine A1 receptor (A1AR) agonists. Here we use the potent…
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2015
2015
The infarct-sparing effect of IB-MECA against myocardial ischemia/reperfusion injury in mice is mediated by sequential activation of adenosine A3 and A2A receptors
Yikui Tian
,
Melissa A. Marshall
,
B. A. French
,
J. Linden
,
Zequan Yang
Basic Research in Cardiology
2015
Corpus ID: 28822703
Conflicting results exist regarding the role of A3 adenosine receptors (A3ARs) in mediating cardioprotection during reperfusion…
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2014
2014
Increased A3AR-dependent Vasoconstriction in Diabetic Mice Is Promoted by Myeloperoxidase
S. Nishat
,
A. Klinke
,
S. Baldus
,
L. Khan
,
S. Basir
Journal of Cardiovascular Pharmacology
2014
Corpus ID: 45922890
Abstract: Vascular dysfunction importantly contributes to mortality and morbidity in various cardiac and metabolic diseases…
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2014
2014
20 Cardioprotection During Chemotherapy: A Case Study to Understand Intracellular Mechanisms to Combat the Cardiotoxicity of Sunitinib
H. Sandhu
,
S. Cooper
,
+4 authors
H. Maddock
Heart
2014
Corpus ID: 76098744
Tyrosine Kinase inhibitor Sunitinib mediates its apoptotic anti-cancer effects by inhibiting intracellular signalling involved in…
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2006
2006
Generation of adenosine A3 receptor functionally humanized mice for the evaluation of the human antagonists.
K. Yamano
,
M. Inoue
,
S. Masaki
,
M. Saki
,
M. Ichimura
,
M. Satoh
Biochemical Pharmacology
2006
Corpus ID: 42620751
Highly Cited
2005
Highly Cited
2005
The Cross-Species A3 Adenosine-Receptor Antagonist MRS 1292 Inhibits Adenosine-Triggered Human Nonpigmented Ciliary Epithelial Cell Fluid Release and Reduces Mouse Intraocular Pressure
Hui Yang
,
M. Ávila
,
+4 authors
M. Civan
Current Eye Research
2005
Corpus ID: 13776750
Purpose: Antagonists to A3 adenosine receptors (ARs) lower mouse intraocular pressure (IOP), but extension to humans is limited…
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Highly Cited
1997
Highly Cited
1997
Up-regulation of adenosine receptors in the cochlea by cisplatin
M. Ford
,
Z. Nie
,
C. Whitworth
,
L. Rybak
,
V. Ramkumar
Hearing Research
1997
Corpus ID: 31075981
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