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ADIPOR1 gene

Known as: ADIPONECTIN RECEPTOR 1, Adiponectin Receptor 1 Gene, PAQR1 
This gene is involved in hormone binding and signal transduction.
National Institutes of Health

Related topics

Related topics

4 relations
Adiponectin Receptor Protein 1Ligand BindingReceptor SignalingSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Novel osmotin inhibits SREBP2 via the AdipoR1/AMPK/SIRT1 pathway to improve Alzheimer's disease neuropathological deficits
Extensive evidence has indicated that a high rate of cholesterol biogenesis and abnormal neuronal energy metabolism play key… 
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Highly Cited
2015
Highly Cited
2015
Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival
The identification of pathways necessary for photoreceptor and retinal pigment epithelium (RPE) function is critical to uncover… 
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Highly Cited
2011
Highly Cited
2011
Direct Role of Adiponectin and Adiponectin Receptors in Endometrial Cancer: In Vitro and Ex Vivo Studies in Humans
Low adiponectin levels are an independent risk factor for and mediate the effect of obesity on endometrial cancer in epidemiology… 
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Highly Cited
2010
Highly Cited
2010
Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1 interact with plasma saturated fatty acids to modulate insulin resistance.
BACKGROUND Progression of the metabolic syndrome (MetS) is determined by genetic and environmental factors. Gene-environment… 
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Highly Cited
2008
Highly Cited
2008
Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk.
CONTEXT Current epidemiological evidence suggests an association between obesity, hyperinsulinemia, and colorectal cancer risk… 
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Highly Cited
2007
Highly Cited
2007
Antiproliferative effect of adiponectin on MCF7 breast cancer cells: a potential hormonal link between obesity and cancer.
Adiponectin, a hormone secreted by adipose tissue, circulates at high concentrations in human plasma. Paradoxically, plasma… 
Highly Cited
2007
Highly Cited
2007
Growth-inhibitory effect of adiponectin via adiponectin receptor 1 on human breast cancer cells through inhibition of S-phase entry without inducing apoptosis
Adiponectin is one of the most important adipocytokines secreted from adipose tissue. In addition to its effects on glucose and… 
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Highly Cited
2006
Highly Cited
2006
Adiponectin Stimulates RANKL and Inhibits OPG Expression in Human Osteoblasts Through the MAPK Signaling Pathway
Our study indicates that recombinant adiponectin induced RANKL and inhibited OPG expression in human osteoblasts through the… 
Highly Cited
2006
Highly Cited
2006
Salivary gland epithelial cells: a new source of the immunoregulatory hormone adiponectin.
OBJECTIVE Adiponectin is an adipocytokine that displays insulin-sensitizing and immunoregulatory properties. Adipocyte… 
Highly Cited
2004
Highly Cited
2004
Adiponectin receptor 1 gene (ADIPOR1) as a candidate for type 2 diabetes and insulin resistance.
Considerable data support adiponectin as an important adipose-derived insulin sensitizer that enhances fatty acid oxidation and… 
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