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ADENYLOSUCCINATE LYASE

Known as: Lyase, Adenylosuccinate, Adenylosuccinase, N(6)-(1,2-Dicarboxyethyl)AMP AMP-lyase 
An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyzes the conversion of 5'-phosphoribosyl-4-(N-succinocarboxamide)-5… Expand
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Adenylosuccinate lyase ADSL) deficiency is a defect of purine metabolism affecting purinosome assembly and reducing metabolite… Expand
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2014
2014
Cerebellar hypoplasia (CH) refers to a cerebellum with a reduced volume, and is a common, but non-specific neuroimaging finding… Expand
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2008
2008
Adenylosuccinate lyase (ADSL) catalyzes two steps in purine nucleotide metabolism-the 8th step in the de novo pathway: conversion… Expand
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Review
2006
Review
2006
Adenylosuccinate lyase deficiency is a disease of purine metabolism which affects patients both biochemically and behaviorally… Expand
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2000
2000
Adenylosuccinate lyase (ADSL) deficiency (MIM 103050) is an autosomal recessive inborn error of purine synthesis characterized by… Expand
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2000
2000
BACKGROUND Adenylosuccinate lyase is an enzyme that plays a critical role in both cellular replication and metabolism via its… Expand
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2000
2000
Adenylosuccinate lyase catalyzes two separate reactions in the de novo purine biosynthetic pathway. Through its dual action in… Expand
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1992
1992
We have examined the molecular basis of three cases of severe mental retardation with autistic features in one family. A point… Expand
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1986
1986
Patients with inherited adenylosuccinase deficiency excrete large quantities of succinyloaminoimidazolecarboxamide riboside… Expand
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1983
1983
In cancer cells, a marked imbalance in the enzymic pattern of purine metabolism is linked with transformation and/or progression… Expand
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