ADAMTS4 gene

Known as: KIAA0688, ADAMTS4, ADAM metallopeptidase with thrombospondin type 1 motif 4 
 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Brain tumors, in particular glioblastomas, have a high morbidity and mortality, mainly due to their invasive nature. A… (More)
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2005
2005
OBJECTIVE To investigate the mechanism of aggrecanolysis in interleukin-1 (IL-1)-treated cartilage tissue by examining the time… (More)
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Highly Cited
2004
Highly Cited
2004
The adamalysin-thrombospondin (ADAMTS) proteinases are a relatively newly described branch of the metzincin family that contain… (More)
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Highly Cited
2004
Highly Cited
2004
C-terminal truncation of ADAMTS-4 from the p68 form to the p53 form is required for activation of its capacity to cleave the Glu… (More)
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2004
2004
A member of the A disintegrin and metalloproteinase domain with thrombospondin type-1 motifs (ADAMTS-4) protease family can… (More)
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2004
2004
Human brain tissue from cerebellum and hippocampus was obtained between 2 h and 24 h post mortem and, after extraction in the… (More)
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2004
2004
ADAMTS4 (aggrecanase-1), a secreted enzyme belonging to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin… (More)
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Highly Cited
2002
Highly Cited
2002
Proteolysis of the hyalectans (aggrecan, versican, brevican) in vivo appears to result from the activity of ADAMTS4 (aggrecanase… (More)
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Highly Cited
2001
Highly Cited
2001
ADAMTS4 (aggrecanase-1) is considered to play a key role in the degradation of aggrecan in arthritides. The inhibitory activity… (More)
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Highly Cited
2000
Highly Cited
2000
Brevican is a member of the lectican family of chondroitin sulfate proteoglycans that is predominantly expressed in the central… (More)
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