Skip to search formSkip to main contentSkip to account menu

ADAMTS4 gene

Known as: KIAA0688, ADAMTS4, ADAM metallopeptidase with thrombospondin type 1 motif 4 
National Institutes of Health

Related topics

Related topics

2 relations
ADAMTS2 geneADAMTS4 Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Structural modeling of osteoarthritis ADAMTS4 complex with its cognate inhibitory protein TIMP3 and rational derivation of cyclic peptide inhibitors from the complex interface to target ADAMTS4.
2018
2018
Association of ADAMTS4 and ADAMTS9 levels with cardiovascular risk in patients with primary hyperparathyroidism
ABSTRACT Purpose: Primary hyperparathyroidism (PHPT) has been associated with increased incidence of morbidity and mortality of… 
2018
2018
Host-produced ADAMTS4 Inhibits Early-Stage Tumor Growth.
Several research groups demonstrated that 'a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs (ADAMTS… 
2018
2018
The role of ADAMTS4 and ADAMTS9 in cardiovascular disease in premature ovarian insufficiency and idiopathic hypogonadotropic hypogonadism
PurposeWe aimed to determine the relation of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS4), and a… 
2017
2017
Promoter methylation status of the TIMP2 and ADAMTS4 genes and patellar tendinopathy.
2016
2016
Identification of Potent Virtual Leads Specific to S1' Loop of ADAMTS4: Pharmacophore Modeling, 3D-QSAR, Molecular Docking and Dynamic Studies.
ADAMTS4 (Aggrecanase-1) is an important enzyme, which belongs to ADAMTS family. Aggrecanase-1 is involved in aggrecan degradation… 
2015
2015
Induction of human ADAMTS-2 gene expression by IL-1α is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells.
2008
2008
Specific inhibition of procollagen C-endopeptidase activity by synthetic peptide with conservative sequence found in chordin.
Procollagen C-endopeptidase (BMP-1) and N-endopeptidase (ADAMTS-2) are key enzymes for correct and efficient conversion of… 
Highly Cited
2002
Highly Cited
2002
ADAMTS4 Cleaves at the Aggrecanase Site (Glu373-Ala374) and Secondarily at the Matrix Metalloproteinase Site (Asn341-Phe342) in the Aggrecan Interglobular Domain*
Two major proteolytic cleavages, one at NITEGE373↓A374RGSVI and the other at VDIPEN341↓F342FGVGG, have been shown to occur in… 
2000
2000
Characterization of 5′-flanking region of human aggrecanase-1 (ADAMTS4) gene
Aggrecanase-1, also known as ADAMTS4 (a disintegrin and metalloproteinase with thrombospondin motifs 4), cleaves at the Glu373… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)