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ADAMTS4 Protein

Known as: ADAMTS 4 Protein, A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein, Aggrecanase 1 
An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may… 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Introduction Intervertebral disc degeneration is thought to contribute to low back pain, however, the pathophysiological… 
2011
2011
  • Li Yu
  • 2011
  • Corpus ID: 76359937
Objective To test the hypothesis that aggrecanase-1 and tissue inhibitors of metalloproteinases-3(TIMP-3)play important role via… 
2009
2009
  • 2009
  • Corpus ID: 27232307
INTRODUCTION: The degradation of aggrecan during osteoarthritis (OA) is catalyzed by increased activities of matrix… 
2006
2006
Summary Interleukin-1 (IL-1β) is the main proinflammatory cytokine stimulant of cartilagedegeneration in arthritis. Aggrecanases… 
2005
2005
Thesis (Ph. D.)--Massachusetts Institute of Technology, Biological Engineering Division, 2005. 
Review
2005
Review
2005
© 2005 CMA Media Inc. Can J Surg, Vol. 48, Suppl., August 2005 — Abstracts 13 determine validity, reliability and precision of… 
2004
2004
  • 2004
  • Corpus ID: 13870055
INTRODUCTION Aggrecanase-1 (ADAMTS-4), a member of the “a disintegrin and metalloproteinase with thrombospondin motifs” (ADAMTS… 
2003
2003
Patients who have sustained a traumatic joint injury, such as a ligament rupture or cartilage fracture, are known to have an… 
2002
2002
  • Tsuji
  • 2002
  • Corpus ID: 36896553
Introduction In human, the notochordal cells typically disappear by the second decade, the time which coincide with the…