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ACROSIN

Known as: Acrosin [Chemical/Ingredient], proteinase, Acrosomal, Akrosin 
A trypsin-like enzyme of spermatozoa which is not inhibited by alpha 1 antitrypsin.
National Institutes of Health

Related topics

Related topics

13 relations
ACR geneAcrosin:EntCat:Pt:Spermatozoa:QnAcrosomeIn Blood

Broader (2)

Serine EndopeptidasesSerine Proteases

Narrower (1)

ninhibin

Papers overview

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Highly Cited
2020
Highly Cited
2020
Acrosin is essential for sperm penetration through the zona pellucida in hamsters
Significance Mammalian oocytes are surrounded by the zona pellucida, a glycoprotein coat that protects the oocyte and embryo from… 
Highly Cited
1998
Highly Cited
1998
Acrosin Accelerates the Dispersal of Sperm Acrosomal Proteins during Acrosome Reaction*
Using homologous recombination, we have previously produced male mice carrying a disruptive mutation (Acr −/−) in the acrosin… 
Highly Cited
1997
Highly Cited
1997
Spermatozoa lacking acrosin protein show delayed fertilization
Acrosin (ACR), a serine proteinase located in the acrosome of the sperm, has been presumed to be involved in the recognition and… 
Highly Cited
1994
Highly Cited
1994
Sperm from mice carrying a targeted mutation of the acrosin gene can penetrate the oocyte zona pellucida and effect fertilization.
Highly Cited
1987
Highly Cited
1987
Identification of a zona-binding protein from boar spermatozoa as proacrosin.
Review
1984
Review
1984
THE IMPORTANCE OF HYDROLYTIC ENZYMES TO AN EXOCYTOTIC EVENT, THE MAMMALIAN SPERM ACROSOME REACTION
The mammalian sperm acrosome reaction is a unique form of exocytosis, which includes the loss of the involved membranes. Other… 
Highly Cited
1981
Highly Cited
1981
Localization of cholesteryl sulfate in human spermatozoa in support of a hypothesis for the mechanism of capacitation.
Cholesteryl sulfate is a normal constituent of human spermatozoa. The in vitro uptake of tritiated cholesteryl sulfate resulted… 
Highly Cited
1977
Highly Cited
1977
Boar proacrosin. Purification and preliminary activation studies of proacrosin isolated from ejaculated boar sperm.
Highly Cited
1972
Highly Cited
1972
Acrosomal Proteinase and Proteinase Inhibitor of Human Spermatozoa
The acrosomal proteinase of human spermatozoa was characterized and differs from other human proteinases. The enzyme has optimal… 
Highly Cited
1972
Highly Cited
1972
Cytochemical demonstration of acrosomal proteinase in mammalian and avian spermatozoa by a silver proteinate method.
A silver proteinate method developed by Takamatsu ci’ at. (1963) was employed for visual demonstration of the active sites of… 
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