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Development of an assay to assess the functional integrity of the human sperm membrane and its relationship to other semen characteristics.
- R. Jeyendran, H. van der Ven, M. Perez-Pelaez, B. Crabo, L. Zaneveld
- Biology, MedicineJournal of reproduction and fertility
The hypoosmotic swelling technique to evaluate the functional integrity of the sperm membrane appears to give high repeatability and accuracy and is closely correlated to the in-vitro fertilizing ability of spermatozoa.
Chemistry and pharmacology of the citrus bioflavonoid hesperidin
No signs of toxicity have been observed with the normal intake of hesperidin or related compounds.
Properties of a new acid-buffering bioadhesive vaginal formulation (ACIDFORM).
A simple, clinical assay to evaluate the acrosin activity of human spermatozoa.
Preliminary experiments indicate that the average sperm acrosin activity of ejaculates whose spermatozoa successfully fertilize human eggs in vitro is significantly higher than those that do not fertilize eggs.
Preclinical evaluation of sodium cellulose sulfate (Ushercell) as a contraceptive antimicrobial agent.
Preclinical studies of the biological properties of sodium cellulose sulfate (Ushercell) currently being developed for use as a topical contraceptive antimicrobial agent suggest that the antimicrobial effects of Ushercell are selective, and not likely mediated by nonspecific cytotoxic mechanisms.
The hypoosmotic swelling test: an update.
This review is an attempt to clarify and update the usefulness of the HOS test as a tool to evaluate the sperm function.
Laser-Induced Thermal Damage of Skin
Abstract : A computerized model was developed for predicting thermal damage of skin by laser exposures. THERMAL, OPTICAL, AND PHYSIOLOGICAL DATA ARE PRESENTED FOR THE MODEL. Model predictions of…
Papillomavirus Microbicidal Activities of High-Molecular-Weight Cellulose Sulfate, Dextran Sulfate, and Polystyrene Sulfonate
The data indicate that the polysulfated andpolysulfonated compounds may be useful nontoxic microbicidal compounds that are active against a variety of sexually transmitted disease agents including papillomaviruses.
Candidate Topical Microbicides Bind Herpes Simplex Virus Glycoprotein B and Prevent Viral Entry and Cell-to-Cell Spread
The results indicate that PRO 2000, polystyrene sulf onate, cellulose sulfate, and polymethylenehydroquinone sulfonate inhibit HSV infection 10,000-fold and are active against clinical isolates, including an acyclovir-resistant variant.