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ABCC3 gene

Known as: MLP2, ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 Gene, MRP3 
This gene is involved in bile metabolism.
National Institutes of Health

Related topics

Related topics

6 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
[The analysis of the association of the polymorphic variants of the TPMT, COMT, and ABCC3 genes with the development of hearing disorders induced by the cisplatin treatment].
Cisplatin and its derivatives are widely used chemotherapeutic agents for the treatment of many cancers, including hepatoblastoma… 
2014
2014
The association of ABCC3 promoter methylation with clopidogrel response in Chinese ischemic stroke patients.
Multidrug resistance protein 3 (MRP3), encoded by ABCC3, is an ATP-dependent efflux pump mediating the transport of many drugs… 
2013
2013
Efffect of the ABCC3 –211C/T polymorphism on clopidogrel responsiveness in patients with percutaneous coronary intervention
Multidrug resistance protein 3 (MPR3), encoded by the ATP‐binding cassette, subfamily C (CFTR/MRP), member 3 (ABCC3) gene… 
2012
2012
Are circulating autoantibodies to ABCC3 transporter a potential biomarker for lung cancer?
PurposeThe present study was undertaken to test circulating autoantibody to ATP-binding cassette C3 (ABCC3) transporter in order… 
2010
2010
Down-regulation of lipids transporter ABCA1 increases the cytotoxicity of Nitidine
PurposeNitidine (NTD) cytotoxicity is highly specific for A549 human lung adenocarcinoma cells. We hypothesized that this… 
2009
2009
ABCC2, ABCC3, and ABCB1, but not CYP3A, Protect against Trabectedin-Mediated Hepatotoxicity
Purpose: Trabectedin (Yondelis, ET-743) is a novel anticancer drug with potent activity against various tumors. However, dose… 
2009
2009
mRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death
Increased activity of multidrug resistance (MDR) genes has been associated with treatment failure in acute leukemias, although… 
Review
2007
Review
2007
Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice
The MRP family is composed of nine transporters, at least eight of which are lipophilic anion transporters that are capable of… 
2006
2006
In acute leukemia, the polymorphism -211C>T in the promoter region of the multidrug resistance-associated protein 3 (MRP3) does not determine the expression level of the gene.
In their intriguing study of polymorphisms of the MRP3 gene, Lang et al. [2] show that the single nucleotide polymorphism (SNP… 
Highly Cited
2005
Highly Cited
2005
Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene
MRP3 is an ABC transporter localized in the basolateral membrane of epithelial cells such as hepatocytes and enterocytes. In this… 
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