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AA 673

Known as: AA-673 
National Institutes of Health

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amlexanox

Papers overview

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1990
1990
Pharmacodynamics of Amlexanox (AA-673) in normal and anaphylactic rat conjunctiva and its effect on histamine concentration.
The pharmacodynamics of Amlexanox (AA-673), an azoxanthone derivative recently developed as an ocular anti-allergic drug, were… 
1989
1989
[Inhibitory effect of amlexanox (AA-673) on the immunological and non-immunological release of histamine or leukotrienes].
The effect of amlexanox on the non-immunological or immunological release of histamine or leukotrienes (LTs) from passively… 
1989
1989
[Inhibitory effect of AA-673 eye drops on ocular provocation for Japanese cedar pollinosis].
The inhibitory effect of 0.25% AA-673 eye drops on histamine release in tears was examined by an ocular provocation test with… 
1989
1989
[Influences of anti-allergic drugs on superoxide generation from the hypoxanthine-xanthine oxidase system or polymorphonuclear leukocytes].
The influences of anti-allergic drugs on superoxide generation from the hypoxanthine-xanthine oxidase system or polymorphonuclear… 
1989
1989
Treatment for intractable perennial allergic rhinitis with AA-673 tablets.
The therapeutic effect and the safety of AA-673 tablets were studied in 31 patients with intractable perennial allergic rhinitis… 
1988
1988
Clinical effect of AA-673 tablets in allergic rhinitis.
Twenty patients with perennial allergic rhinitis were treated with AA-673 tablets for a mean period of 66 days.Based on the final… 
Highly Cited
1987
Highly Cited
1987
Mechanism of action of an antiallergic agent, amlexanox (AA-673), in inhibiting histamine release from mast cells. Acceleration of cAMP generation and inhibition of phosphodiesterase.
Amlexanox markedly inhibits histamine release from rat mast cells. To clarify the mechanism of this inhibition, we investigated… 
1985
1985
Mechanism of the action of amoxanox (AA-673), an orally active antiallergic agent.
Amoxanox inhibited immunologically stimulated and LTD4-induced bronchoconstriction in laboratory animals. Amoxanox, like DSCG… 
1985
1985
Inhibition by amoxanox (AA-673) of the immunologically, leukotriene D4- or platelet-activating factor-stimulated bronchoconstriction in guinea pigs and rats.
We studied the effects of amoxanox (AA-673) on allergic asthma and spasmogen-induced bronchoconstriction in guinea pigs and rats… 
Highly Cited
1985
Highly Cited
1985
Synthesis of the metabolites and degradation products of 2-amino-7-isopropyl-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3- carboxylic acid (Amoxanox).
The metabolites and degradation products of 2-amino-7-isopropyl-5-oxo-5H-[1] benzopyrano-[2, 3-b] pyridine-3-carboxylic acid… 
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