A 771726

Known as: a 77-1726, A77 1726, A-771726 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
051019932017

Papers overview

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2010
2010
BACKGROUND The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and… (More)
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2010
2010
The immunomodulatory drug leflunomide is frequently used for treating polyomavirus-associated nephropathy, yet its antiviral… (More)
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2010
2010
BACKGROUND Human BK polyomavirus is the causative agent of BK nephropathy which is now the leading cause of early renal graft… (More)
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2001
2001
Leflunomide is a new immunosuppressive drug whose active metabolite, A77 1726, impairs cellular nucleotide metabolism by… (More)
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1998
1998
Leflunomide is currently in phase-III clinical trials for the treatment of rheumatoid arthritis. In this study, we have focused… (More)
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1997
1997
The immunosuppressive metabolite of leflunomide, A77 1726, inhibits the enzymatic activity of protein tyrosine kinases and of… (More)
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Highly Cited
1996
Highly Cited
1996
The active metabolite of leflunomide. A771726, is a novel immunosuppressive compound that has been shown to be a powerful… (More)
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1995
1995
A protein with high affinity (Kd 12 nM) for the immunomodulatory compound A77 1726 has been isolated from mouse spleen and… (More)
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1995
1995
Leflunomide [HWA 486 or RS-34821, 5-methyl-N-(4-trifluoromethylphenyl)-4-isoxazole carboximide] is an immunosuppressive agent… (More)
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1993
1993
The active metabolite of leflunomide, A77 1726 inhibits the proliferation of a variety of mammalian cell lines in culture… (More)
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