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A 62176

Known as: A-62176 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

OxazinesQuinolonesTopoisomerase II Inhibitors

Papers overview

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2008
2008
New insight for fluoroquinophenoxazine derivatives as possibly new potent topoisomerase I inhibitor.
2003
2003
Design, synthesis, and evaluation of psorospermin/quinobenzoxazine hybrids as structurally novel antitumor agents.
Topoisomerase II, an enzyme that catalyzes changes in the topology of DNA, plays several key roles in DNA metabolism and… 
1999
1999
Structural Insight into a Quinolone-Topoisomerase II-DNA Complex
Quinobenzoxazine A-62176, developed from the antibacterial fluoroquinolones, is active in vitro andin vivo against murine and… 
1999
1999
The quinobenzoxazines: relationship between DNA binding and biological activity.
The quinobenzoxazine compounds, derived from antibacterial quinolones, is active in vitro and in vivo against murine and human… 
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