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A 285222

Known as: A-285222, A285222 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

A 185 cpd

Broader (1)

Pyrazoles

Papers overview

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2018
2018
In vivo inhibition of nuclear factor of activated T-cells leads to atherosclerotic plaque regression in IGF-II/LDLR–/–ApoB100/100 mice
Aims: Despite vast clinical experience linking diabetes and atherosclerosis, the molecular mechanisms leading to accelerated… 
2015
2015
Streptococcal M1 protein triggers chemokine formation, neutrophil infiltration, and lung injury in an NFAT‐dependent manner
Streptococcus pyogenes of the M1 serotype can cause STSS, which is associated with significant morbidity and mortality. The… 
2014
2014
High glucose enhances store-operated calcium entry by upregulating ORAI/STIM via calcineurin-NFAT signalling
ORAI and stromal interaction molecule (STIM) are store-operated channel molecules that play essential roles in human physiology… 
2009
2009
Diabetic Vascular Complications & Inflammation - role of NFAT and TNFalpha
Vascular complications of diabetes account for the majority of morbidity and mortality among diabetic patients. Large clinical… 
2006
2006
NOVEL BLOCKER OF NFAT ACTIVATION INHIBITS INTERLEUKIN-6 PRODUCTION IN HUMAN MYOMETRIAL ARTERIES AND REDUCES VASCULAR SMOOTH MUSCLE CELL PROLIFERATION
The calcineurin/NFAT signaling pathway has been found to play a role in regulating growth and differentiation in several cell… 
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