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9-cis-retinoic acid biosynthesis

Known as: 9-cis-retinoic acid synthesis, 9-cis-retinoic acid formation, 9-cis-retinoic acid biosynthetic process 
The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative. [GOC:jl, PMID… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
This study describes cDNA cloning and characterization of mouse RALDH4. The 2.3-kb cDNA encodes an aldehyde dehydrogenase of 487… Expand
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2002
2002
It has been proposed that cis-retinol dehydrogenase (cRDH) acts within the body to catalyze the oxidation of 9-cis-retinol, an… Expand
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2002
2002
9-cis-Retinoic acid activates retinoid X receptors, which serve as heterodimeric partners with other nuclear hormone receptors… Expand
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2000
2000
Retinoids function through conformational alterations of ligand-dependent nuclear transcription factors, the retinoic acid… Expand
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Highly Cited
2000
Highly Cited
2000
  • M. Lin, J. Napoli
  • The Journal of Biological Chemistry
  • 2000
  • Corpus ID: 24454268
This report describes the isolation of a heretofore uncharacterized aldehyde dehydrogenase (ALDH) with retinal dehydrogenase… Expand
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1999
1999
We have identified a retinol dehydrogenase (cRDH) that catalyzes the oxidation of 9-cis- but not all-trans-retinol and proposed… Expand
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Highly Cited
1997
Highly Cited
1997
All-trans- and 9-cis-retinoic acid are active retinoids for regulating expression of retinoid responsive genes, serving as… Expand
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