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8-nitroguanine

National Institutes of Health

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2 relations

Broader (1)

Guanine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Pathogenesis of oral lichen planus--a review.
Oral lichen planus (OLP) is a T-cell-mediated chronic inflammatory oral mucosal disease of unknown etiology. OLP presents as… Expand
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Review
2006
Review
2006
Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation.
Peroxynitrite induces DNA base damage predominantly at guanine (G) and 8-oxoguanine (8-oxoG) nucleobases via oxidation reactions… Expand
Review
2006
Review
2006
Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis
Abstract Infection and chronic inflammation are proposed to contribute to carcinogenesis through inflammation-related mechanisms… Expand
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Review
2006
Review
2006
8-nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species: formation, occurrence, and implications in inflammation and carcinogenesis.
The authors review studies on 8-nitroguanine (8-NO(2)-G) formed by reactions of guanine, guanosine, and 2 - deoxyguanosine… Expand
Highly Cited
2004
Highly Cited
2004
Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase.
Chronic inflammation induced by repeated infection with Opisthorchis viverrini has been postulated to be a risk factor for… Expand
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Highly Cited
2003
Highly Cited
2003
8-nitroguanine formation in the liver of hamsters infected with Opisthorchis viverrini.
Nucleic acid damage by reactive nitrogen and oxygen species may contribute to the carcinogenesis associated with chronic… Expand
Review
1997
Review
1997
DNA damage induced by peroxynitrite: subsequent biological effects.
Nitric oxide (NO) and superoxide rapidly react to yield peroxynitrite. Peroxynitrite is a potent oxidant which reacts with… Expand
Highly Cited
1996
Highly Cited
1996
Effects of carbon dioxide/bicarbonate on induction of DNA single‐strand breaks and formation of 8‐nitroguanine, 8‐oxoguanine and base‐propenal mediated by peroxynitrite
Carbon dioxide has been reported to react with peroxynitrite (ONOO−), a strong oxidant and nitrating agent, to form an ONO2CO2… Expand
Highly Cited
1995
Highly Cited
1995
Formation of 8-nitroguanine by the reaction of guanine with peroxynitrite in vitro.
Nitric oxide and superoxide anion, both formed in inflamed tissues, react rapidly to form the peroxynitrite anion (ONOO-), a… Expand
Highly Cited
1995
Highly Cited
1995
Formation of 8‐nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination
Peroxynitrite is a strong oxidant formed by reaction of nitric oxide with superoxide in inflamed tissues. We have demonstrated… Expand
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