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8-nitroguanine

National Institutes of Health

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Broader (1)

Guanine
analogs & derivatives

Papers overview

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2015
2015
Nonylphenol exposure is associated with oxidative and nitrative stress in pregnant women
ABSTRACT Animal studies have shown that exposure to nonylphenol (NP) increases oxidative/nitrative stress, but whether it does so… 
2013
2013
Protection by taurine against INOS-dependent DNA damage in heavily exercised skeletal muscle by inhibition of the NF-κB signaling pathway.
Taurine protects against tissue damage in a variety of models involving inflammation, especially the muscle. We set up a heavy… 
2011
2011
Nitrative and oxidative DNA damage caused by K-ras mutation in mice.
2010
2010
Formation of 8-nitroguanine due to reaction between guanyl radical and nitrogen dioxide: catalytic role of hydration.
8-Nitroguanine (8-NitroG) is known to be a potent mutagenic product obtained from the guanine base of DNA that induces GC to AT… 
2009
2009
Mutagenic product formation due to reaction of guanine radical cation with nitrogen dioxide.
The reaction between nitrogen dioxide (NO2*) and guanine radical cation (G*+) yielding the mutagenic product 8-nitroguanine… 
2005
2005
In Situ Sensing of DNA Damage by a Nitric Oxide‐Releasing Compound
Abstract Oxidative stress can be caused by in vivo chemical generation of reactive oxygen species (ROS) and reactive nitrogen… 
2002
2002
Photochemically catalyzed generation of site-specific 8-nitroguanine adducts in DNA by the reaction of long-lived neutral guanine radicals with nitrogen dioxide.
A novel photochemical approach is described for synthesizing site-specific 8-nitro-2'-deoxyguanosine (8-nitro-dG) adducts DNA… 
2002
2002
Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor.
2001
2001
Gaseous nitric oxide-induced 8-nitroguanine formation in human lung fibroblast cells and cell-free DNA.
A time- and dose-dependent increase in 8-nitroguanine (8-NO(2)-G) was observed in human lung fibroblast cells (MRC-5) after… 
1999
1999
Formation of 8-nitroguanine from 2'-deoxyguanosine by NO/O2 system.
We investigated the reaction of 2'-deoxyguanosine (dGuo) with NO/O2 gas mixture under physiological condition and detected 8… 
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