8-nitroguanine

Abstract Infection and chronic inflammation are proposed to contribute to carcinogenesis through inflammation-related mechanisms… Expand

Peroxynitrite induces DNA base damage predominantly at guanine (G) and 8-oxoguanine (8-oxoG) nucleobases via oxidation reactions… Expand

BACKGROUND/AIMS Nucleic acid damage by reactive nitrogen and oxygen species may contribute to inflammation-related carcinogenesis… Expand

Chronic inflammation induced by repeated infection with Opisthorchis viverrini has been postulated to be a risk factor for… Expand

Helicobacter pylori infection causes chronic inflammation, which can lead to gastric carcinoma. A double immunofluorescence… Expand

Nucleic acid damage by reactive nitrogen and oxygen species may contribute to the carcinogenesis associated with chronic… Expand

Carbon dioxide has been reported to react with peroxynitrite (ONOO−), a strong oxidant and nitrating agent, to form an ONO2CO2… Expand

Exposure of isolated calf thymus DNA and human skin epidermal keratinocytes to peroxynitrite or the peroxynitrite generator, 3… Expand

Peroxynitrite is a strong oxidant formed by reaction of nitric oxide with superoxide in inflamed tissues. We have demonstrated… Expand

Nitric oxide and superoxide anion, both formed in inflamed tissues, react rapidly to form the peroxynitrite anion (ONOO-), a… Expand