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8-nitroguanine

National Institutes of Health

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2 relations

Broader (1)

Guanine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Protection by taurine against INOS-dependent DNA damage in heavily exercised skeletal muscle by inhibition of the NF-κB signaling pathway.
Taurine protects against tissue damage in a variety of models involving inflammation, especially the muscle. We set up a heavy… 
2011
2011
Nitrative and oxidative DNA damage caused by K-ras mutation in mice.
2010
2010
Formation of 8-nitroguanine due to reaction between guanyl radical and nitrogen dioxide: catalytic role of hydration.
8-Nitroguanine (8-NitroG) is known to be a potent mutagenic product obtained from the guanine base of DNA that induces GC to AT… 
2009
2009
Immunohistochemical analysis of 8-nitroguanine, a nitrative DNA lesion, in relation to inflammation-associated carcinogenesis.
Chronic inflammation is induced by various infectious/infected agents and by many physical, chemical and immunological factors… 
2002
2002
Photochemically catalyzed generation of site-specific 8-nitroguanine adducts in DNA by the reaction of long-lived neutral guanine radicals with nitrogen dioxide.
A novel photochemical approach is described for synthesizing site-specific 8-nitro-2'-deoxyguanosine (8-nitro-dG) adducts DNA… 
2002
2002
Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor.
2001
2001
Gaseous nitric oxide-induced 8-nitroguanine formation in human lung fibroblast cells and cell-free DNA.
A time- and dose-dependent increase in 8-nitroguanine (8-NO(2)-G) was observed in human lung fibroblast cells (MRC-5) after… 
Highly Cited
1999
Highly Cited
1999
8-Nitro-2'-deoxyguanosine, a specific marker of oxidation by reactive nitrogen species, is generated by the myeloperoxidase-hydrogen peroxide-nitrite system of activated human phagocytes.
Reactive intermediates generated by phagocytes damage DNA and may contribute to the link between chronic inflammation and cancer… 
1999
1999
Formation of 8-nitroguanine from 2'-deoxyguanosine by NO/O2 system.
We investigated the reaction of 2'-deoxyguanosine (dGuo) with NO/O2 gas mixture under physiological condition and detected 8… 
Highly Cited
1996
Highly Cited
1996
Base modification and strand breakage in isolated calf thymus DNA and in DNA from human skin epidermal keratinocytes exposed to peroxynitrite or 3-morpholinosydnonimine.
Exposure of isolated calf thymus DNA and human skin epidermal keratinocytes to peroxynitrite or the peroxynitrite generator, 3… 
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