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Oral lichen planus (OLP) is a T-cell-mediated chronic inflammatory oral mucosal disease of unknown etiology. OLP presents as… Expand Peroxynitrite induces DNA base damage predominantly at guanine (G) and 8-oxoguanine (8-oxoG) nucleobases via oxidation reactions… Expand Abstract Infection and chronic inflammation are proposed to contribute to carcinogenesis through inflammation-related mechanisms… Expand The authors review studies on 8-nitroguanine (8-NO(2)-G) formed by reactions of guanine, guanosine, and 2 - deoxyguanosine… Expand Chronic inflammation induced by repeated infection with Opisthorchis viverrini has been postulated to be a risk factor for… Expand Nucleic acid damage by reactive nitrogen and oxygen species may contribute to the carcinogenesis associated with chronic… Expand Nitric oxide (NO) and superoxide rapidly react to yield peroxynitrite. Peroxynitrite is a potent oxidant which reacts with… Expand Carbon dioxide has been reported to react with peroxynitrite (ONOO−), a strong oxidant and nitrating agent, to form an ONO2CO2… Expand Nitric oxide and superoxide anion, both formed in inflamed tissues, react rapidly to form the peroxynitrite anion (ONOO-), a… Expand Peroxynitrite is a strong oxidant formed by reaction of nitric oxide with superoxide in inflamed tissues. We have demonstrated… Expand