8-nitroguanine

Peroxynitrite induces DNA base damage predominantly at guanine (G) and 8-oxoguanine (8-oxoG) nucleobases via oxidation reactions… (More)

Oral leukoplakia is a premalignant lesion associated with development of oral cancer. To clarify the mechanism of development of… (More)

Infection and chronic inflammation are proposed to contribute to carcinogenesis through inflammation-related mechanisms… (More)

8-Nitro-2'-deoxyguanosine (8-NO(2)-dG) DNA adducts are induced by the reactive nitrogen species and may be associated with the… (More)

Chronic inflammation induced by repeated infection with Opisthorchis viverrini has been postulated to be a risk factor for… (More)

Helicobacter pylori infection causes chronic inflammation, which can lead to gastric carcinoma. A double immunofluorescence… (More)

Nucleic acid damage by reactive nitrogen and oxygen species may contribute to the carcinogenesis associated with chronic… (More)

Carbon dioxide has been reported to react with peroxynitrite (ONOO-), a strong oxidant and nitrating agent, to form an ONO2CO2… (More)

Nitric oxide and superoxide anion, both formed in inflamed tissues, react rapidly to form the peroxynitrite anion (ONOO-), a… (More)

Peroxynitrite is a strong oxidant formed by reaction of nitric oxide with superoxide in inflamed tissues. We have demonstrated… (More)