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8-azaxanthine

National Institutes of Health

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Xanthines

Papers overview

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1981
1981
Specific resistance to 8-azaguanine in cells with normal hypoxanthine phosphoribosyltransferase (HPRT) activity: the role of guanine deaminase.
The role of guanine deaminase in selective cellular resistance to 8-azaguanine was examined, using eight mammalian cell lines and… 
1980
1980
Differences between rat liver epithelial cells and fibroblast cells in sensitivity to 8-azaguanine
SummaryEpithelial and fibroblast cells from adult rat liver were found to differ markedly in their sensitivities to the toxic… 
1976
1976
Complexes of poly(adenylic acid) with complementary monomers.
The interaction of a number of potentially complementary monomers with poly(A) has been investigated by equilibrium dialysis… 
1970
1970
The toxicity of adenine and of purine-analogs to 2,6-diamino-purine-sensitive and -resistant L-strain mouse cells.
The toxicity of adenine, hypoxanthine, and several purine-analogs to 2,6-diaminopurine (DAP)-resistant (DAP-r) and -sensitive… 
1964
1964
Action of 8-azaguanine and 8-azaxanthine on Pseudomonas aeruginosa.
Hokin, L. E. & Hokin, M. R. (1959b). J. biol. Chem. 234, 1387. Ingle, D. J. (1954). Acta endocr., Kbh., 17, 172. Jones, M. E… 
1957
1957
Searches for exploitable biochemical differences between normal and cancer cells. III. Effects of aminoimidazolecarboxamide on purine metabolism.
nucleic acid guanine (1, 4, 5). One possible ex planation of this observed difference between tu mors and normal tissues might be… 
1957
1957
The effect of metabolite analogues on growth of Bacillus anthracis in the guinea pig and on the formation of virulence-determining factors.
SUMMARY: Several metabolite analogues have been tested for their effect on the growth of Bacillus anthracis and its ability to… 
1955
1955
GUANINE DEGRADATION BY CLOSTRIDIUM ACIDIURICI I
Clostridium acidiuri strain 9a has been shown by Barker and Beck (1941) to be able to decompose guanine, xanthine, uric acid, and… 
1952
1952
Combination Chemotherapy of Cancer
Summary 1. 2-Amino-4-hydroxy-6-formyl pteridine (6-formylpteridine), although non-carcinostatic by itself, augmented the… 
1950
1950
The competitive inhibition of uricase activity by 8-azaguanine and by 8-azaxanthine.
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