7-deazapurine
National Institutes of Health
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(51) Int. Cl." ......................... C12O 1/68; A61K 31/519; A61K 48/OO (52) U.S. Cl. ....................... 435/6; 514/262…
Ugarkar et al.—Journal of Medicinal Chemistry 2000, 43(15), pp. 2883-2893. Pudlo et al.—Journal of Medicinal Chemistry, 1988, 31…
A series of cardiac troponin I-interacting kinase (TNNI3K) inhibitors arising from 3-((9H-purin-6-yl)amino)-Nmethyl…
The metabolic degradation of aldehydes is catalyzed by oxidoreductases from which aldehyde dehydrogenases (EC 1.2.1) comprise…
A series of 33 7-deazapurine ribonucleosides bearing an alkyl, aryl or hetaryl group in position 6 and H, F or Cl atom in…
Oligonucleotides with parallel (ps) or antiparallel (aps) chain orientation containing 7-deaza-2′-deoxyisoguanosine (1) or 2…
Steric and stereoelectronic effects of 7- and 8-substituents of 7-deaza-2′-deoxy-adenosine and -guanosine on the dynamic sugar…