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6-thioxanthine

Known as: thioxanthine 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Up to 1/5 of patients with wildtype thiopurine-S-methyltransferase (TPMT) activity prescribed azathioprine (AZA) or… Expand
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2009
2009
An HPLC method has been developed and validated for the rapid determination of mercaptopurine and four of its metabolites… Expand
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2007
2007
In spite of over 40 years of clinical use of 6-mercaptopurine, many aspects of complex pharmacology and metabolism of this drug… Expand
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Highly Cited
1996
Highly Cited
1996
A nonhomologous integration vector was used to identify the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl… Expand
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1996
1996
Genes that encode enzymes that convert inactive "prodrugs" into anticancer metabolites may be therapeutically useful against… Expand
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1996
1996
Antibodies have been raised in rabbits to a chlorpromazine sulfoxide-bovine serum albumin immunogen and the resulting antiserum… Expand
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Highly Cited
1994
Highly Cited
1994
6-Thioxanthine caused 50% inhibition of the growth of Toxoplasma gondii in human fibroblasts at a concentration of 5 micrograms… Expand
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1987
1987
Thioxanthine is toxic for mammalian cells transformed by the dominant selectable marker gpt. It allowed us to select, in the… Expand
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Highly Cited
1985
Highly Cited
1985
The bioavailability of oral mercaptopurine (MP) is poor, and plasma levels following p.o. dosing are highly variable. In an… Expand
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1975
1975
Phenothiazine derivatives were examined as potential antagonists of the inhibitory noradrenergic synapses from the nucleus locus… Expand
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