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6-thioxanthine

Known as: thioxanthine 
National Institutes of Health

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Xanthines

Papers overview

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2010
2010
Kinetics of 6-thioxanthine metabolism by allelic variants of xanthine oxidase.
Our previous studies show that 10 xanthine oxidase (XO) variants (Arg149Cys, Pro555Ser, Arg607Gln, Thr623Ile, Ile703Val Asn909Lys… 
2002
2002
The glutathione-activated thiopurine prodrugs trans-6-(2-acetylvinylthio)guanine and cis-6-(2-acetylvinylthio)purine cause less in vivo toxicity than 6-thioguanine after single- and multiple-dose…
trans-6-(2-Acetylvinylthio)guanine (trans-AVTG) and cis-6-(2-acetylvinylthio)purine (cis-AVTP) are glutathione-activated prodrugs… 
2001
2001
Toxoplasma gondii: mechanism of the parasitostatic action of 6-thioxanthine.
In contrast to the cytocidal effect of 6-thiopurines on mammalian cells, the action of 6-thioxanthine on Toxoplasma gondii was… 
1997
1997
lntracellular thiopurine nucleotides and azathioprine myelotoxicity in organ transplant patients
Aim Despite widespread use of azathioprine in organ transplant recipients, the mechanism of its myelotoxicity remains unclear… 
1996
1996
Direct determination of some phenothiazine sedatives in greyhound urine by fluoroimmunoassay.
Antibodies have been raised in rabbits to a chlorpromazine sulfoxide-bovine serum albumin immunogen and the resulting antiserum… 
1994
1994
PHOTOCHEMICAL SENSITIZATION BY AZATHIOPRINE AND ITS METABOLITES. PART 3. A DIRECT EPR AND SPIN‐TRAPPING STUDY OF LIGHT‐INDUCED FREE RADICALS FROM 6‐MERCAPTOPURINE AND ITS OXIDATION PRODUCTS
Abstract Sunlight has been implicated in the high incidence of skin cancer found in patients receiving 6‐mercaptopurine (PSH) in… 
1993
1993
A hit-and-run system for introducing mutations into the Ig H chain locus of hybridoma cells by homologous recombination.
The traditional method of site-specific mutagenesis is to introduce predetermined mutations into an expression vector, which is… 
1989
1989
Milk could decrease the bioavailability of 6-mercaptopurine.
The bioavailability of 6-mercaptopurine (6-MP) administered orally for maintenance therapy of children with acute lymphoblastic… 
1963
1963
Metabolism of 9-Ethyl-6-MP-S35 and 9-Butyl-6-MP-S35 in Humans.∗
Summary Radioactive 9-B-6-MP-S35 and 9-E-6-MP-S35 were synthesized and administered to patients. The radioactive metabolites in… 
1960
1960
The metabolism of 6-mercaptopurine by Bacillus cereus.
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