6-thioxanthine

Known as: thioxanthine 
 
National Institutes of Health

Papers overview

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2013
2013
Up to 1/5 of patients with wildtype thiopurine-S-methyltransferase (TPMT) activity prescribed azathioprine (AZA) or… Expand
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2009
2009
An HPLC method has been developed and validated for the rapid determination of mercaptopurine and four of its metabolites… Expand
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2001
2001
In contrast to the cytocidal effect of 6-thiopurines on mammalian cells, the action of 6-thioxanthine on Toxoplasma gondii was… Expand
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1999
1999
1. The aim of this study was to investigate 6-mercaptopurine (6MP) metabolism by human liver cytosol in vitro. 2. Cytosol was… Expand
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Highly Cited
1998
Highly Cited
1998
The hypoxanthine-xanthine-guanine phosphoribosyl transferase (HXGPRT) gene of the protozoan parasite Toxoplasma gondii encodes a… Expand
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1997
1997
The identification of transgenes with antitumor activity is critical to the development of gene therapy of cancer. Retrovirus… Expand
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Highly Cited
1996
Highly Cited
1996
A nonhomologous integration vector was used to identify the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl… Expand
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1995
1995
Recently, S-(purin-6-yl)-L-cysteine (GC) was shown to be a kidney-selective prodrug of 6-mercaptopurine. In the present study… Expand
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1994
1994
6-Thioxanthine caused 50% inhibition of the growth of Toxoplasma gondii in human fibroblasts at a concentration of 5 micrograms… Expand
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1985
1985
The bioavailability of oral mercaptopurine (MP) is poor, and plasma levels following p.o. dosing are highly variable. In an… Expand
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