Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

6-pyruvoyltetrahydropterin 2'-reductase activity

Known as: 6-pyruvoyl-tetrahydropterin 2'-reductase activity, 6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity, 6-pyruvoyltetrahydropterin reductase activity 
Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin. [EC:1.1.1.220, MetaCyc:1.1.1.220-RXN… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Objectives To evaluate the cost-benefit of implementing an expanded newborn screening programme for hyperphenylalaninemias due to… Expand
  • figure 1
  • table 1
  • table 3
Is this relevant?
2009
2009
Objective:To report the efficacy, tolerability, and safety of the dopamine agonist pramipexole in a series of 5 patients affected… Expand
  • table 1
Is this relevant?
2009
2009
SummaryNo reports are available about the course of pregnancies in women with tetrahydrobiopterin (BH4) deficiencies or the… Expand
  • figure 1
  • figure 2
Is this relevant?
2008
2008
OBJECTIVE To report the long-term results of early initiation of treatment of 6-pyruvoyl-tetrahydropterin synthase (PTPS… Expand
  • table 1
  • table 2
Is this relevant?
2000
2000
We detected a case of 6-pyruvoyl tetrahydropterin synthase (PTPS) deficiency during a neonatal mass screening and considered the… Expand
Is this relevant?
Review
1993
Review
1993
Abstract Biosynthesis of tetrahydrobiopterin starts from guanosine triphosphate by the action of guanosine triphosphate… Expand
  • figure 1
  • figure 2
  • figure 3
  • table I
  • figure 4
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Interferon-gamma induces tetrahydrobiopterin biosynthesis in human cells and cell lines. Macrophages are peculiar in the… Expand
  • figure 1
  • figure 2
  • table I
  • table II
Is this relevant?
1989
1989
The NADPH-dependent reduction of the two carbonyl groups in the side chain of the first tetrahydropterin intermediate on the… Expand
Is this relevant?
1989
1989
The distribution of GTP-cyclohydrolase I, pyruvoyl tetrahydropterin (dysopropterin) synthase, and pyruvoyl tetrahydropterin… Expand
Is this relevant?
1984
1984
9 partially purified enzyme (Enzyme A) from Drosophila melanogaster Aatalyzes the conversion of 7,8- dihydroneopterin… Expand
Is this relevant?