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6-pyruvoyltetrahydropterin 2'-reductase activity

Known as: 6-pyruvoyl-tetrahydropterin 2'-reductase activity, 6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity, 6-pyruvoyltetrahydropterin reductase activity 
Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin. [EC:1.1.1.220, MetaCyc:1.1.1.220-RXN… Expand
National Institutes of Health

Papers overview

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2012
2012
The enzyme 6-pyruvoyl-tetrahydropterin synthase (PTPS, gene symbol: PTS) is involved in the second step of the de novo… Expand
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2009
2009
Objective: To report the efficacy, tolerability, and safety of the dopamine agonist pramipexole in a series of 5 patients… Expand
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2006
2006
Little information is available on the long‐term course and adult outcome of patients with 6‐pyruvoyl‐tetrahydropterin synthase… Expand
1994
1994
Ammonium sulfate fractionation and standard column chromatography techniques have been used to purify the enzyme sepiapterin… Expand
Review
1993
Review
1993
Abstract Biosynthesis of tetrahydrobiopterin starts from guanosine triphosphate by the action of guanosine triphosphate… Expand
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Highly Cited
1990
Highly Cited
1990
Interferon-gamma induces tetrahydrobiopterin biosynthesis in human cells and cell lines. Macrophages are peculiar in the… Expand
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1990
1990
The distribution of GTP-cyclohydrolase I, pyruvoyl tetrahydropterin (dysopropterin) synthase, and pyruvoyl tetrahydropterin… Expand
1989
1989
The NADPH-dependent reduction of the two carbonyl groups in the side chain of the first tetrahydropterin intermediate on the… Expand
1984
1984
9 partially purified enzyme (Enzyme A) from Drosophila melanogaster Aatalyzes the conversion of 7,8- dihydroneopterin… Expand
1963
1963
The pterins of adult fishes are located in special chromatophores, the “pterinophores”, where they are bound to protein granules… Expand