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6-pyruvoyltetrahydropterin 2'-reductase activity
Known as:
6-pyruvoyl-tetrahydropterin 2'-reductase activity
, 6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity
, 6-pyruvoyltetrahydropterin reductase activity
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Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin. [EC:1.1.1.220, MetaCyc:1.1.1.220-RXN…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Mutation spectrum of and founder effects affecting the PTS gene in East Asian populations
Yen‐Hui Chiu
,
Ying-Chen Chang
,
+13 authors
Tze-tze Liu
Journal of Human Genetics
2012
Corpus ID: 12656932
The enzyme 6-pyruvoyl-tetrahydropterin synthase (PTPS, gene symbol: PTS) is involved in the second step of the de novo…
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2009
2009
Dopamine agonists in 6-pyruvoyl tetrahydropterin synthase deficiency
F. Porta
,
A. Mussa
,
D. Concolino
,
M. Spada
,
A. Ponzone
Neurology
2009
Corpus ID: 29892366
Objective: To report the efficacy, tolerability, and safety of the dopamine agonist pramipexole in a series of 5 patients…
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2006
2006
Long‐term follow‐up and adult outcome of 6‐pyruvoyl‐tetrahydropterin synthase deficiency
E. Roze
,
M. Vidailhet
,
+4 authors
A. Roubergue
Movement Disorders
2006
Corpus ID: 16944388
Little information is available on the long‐term course and adult outcome of patients with 6‐pyruvoyl‐tetrahydropterin synthase…
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Review
2006
Review
2006
Long-term follow-up of Chinese patients who received delayed treatment for 6-pyruvoyl-tetrahydropterin synthase deficiency.
Ni‐Chung Lee
,
Ling-Yee Cheng
,
Tze-tze Liu
,
K. Hsiao
,
P. Chiu
,
D. Niu
Molecular Genetics and Metabolism
2006
Corpus ID: 25014068
Review
1993
Review
1993
Tetrahydrobiopterin and Cytokines
E. Werner
,
G. Werner-Felmayer
,
H. Wachter
Proceedings of the Society for Experimental…
1993
Corpus ID: 22794144
Abstract Biosynthesis of tetrahydrobiopterin starts from guanosine triphosphate by the action of guanosine triphosphate…
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Highly Cited
1990
Highly Cited
1990
Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase…
E. Werner
,
G. Werner-Felmayer
,
+5 authors
H. Wachter
Journal of Biological Chemistry
1990
Corpus ID: 16226416
1989
1989
Immunological studies on the participation of 6-pyruvoyl tetrahydropterin (2'-oxo) reductase, an aldose reductase, in tetrahydrobiopterin biosynthesis.
S. Milstien
,
S. Kaufman
Biochemical and Biophysical Research…
1989
Corpus ID: 36309602
1989
1989
Biosynthetic pathways of pteridines and their association with phenotypic expression in vitro in normal and neoplastic pigment cells from goldfish.
M. Masada
,
J. Matsumoto
,
M. Akino
Pigment Cell Research
1989
Corpus ID: 45482040
The distribution of GTP-cyclohydrolase I, pyruvoyl tetrahydropterin (dysopropterin) synthase, and pyruvoyl tetrahydropterin…
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1984
1984
Intermediates in the enzymic synthesis of tetrahydrobiopterin in Drosophila melanogaster.
A. C. Switchenko
,
J. Primus
,
G. M. Brown
Biochemical and Biophysical Research…
1984
Corpus ID: 26855052
1963
1963
Tetrahydropterin und Melanophoren-Differenzierung bei Fischen
I. Ziegler
1963
Corpus ID: 97556405
The pterins of adult fishes are located in special chromatophores, the “pterinophores”, where they are bound to protein granules…
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