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6-heptyne-2,5-diamine

Known as: methyl-acetylenicputrescine, methylacetylenic putrescine 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

AlkynesAntineoplastic AgentsDiaminesOrnithine Decarboxylase Inhibitors

Narrower (1)

MDL 72175

Papers overview

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2004
2004
Phase I study of methylacetylenic putrescine, an inhibitor of polyamine biosynthesis
SummaryIn a phase I clinical trial, nine patients with advanced malignancies not amenable to alternative therapy received… 
1999
1999
Effects of methylacetylenic putrescine, an ornithine decarboxylase inhibitor and potential novel anticancer agent, on human and mouse cancer cell lines.
Sensitivity of several human and mouse cancer cell lines to methylacetylenic putrescine (MAP) was evaluated using clonogenic… 
Highly Cited
1988
Highly Cited
1988
Polyamines and insulin production in isolated mouse pancreatic islets.
The aim of the present study was to evaluate the role of polyamines in the metabolism and insulin production of pancreatic-islet… 
1984
1984
Polyamines and the development of isolated neurons in cell culture
The possible role of polyamines in the development of isolated neuroblasts from the cerebral cortex of embryonic chick brain was… 
1983
1983
(2R,5R)-6-heptyne-2,5-diamine, an extremely potent inhibitor of mammalian ornithine decarboxylase.
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