6-Phosphofructokinase

Known as: Phosphofructokinase-1 [Chemical/Ingredient], ATP:D-fructose-6-phosphate 1-phosphotransferase, Phosphofructokinase 1 
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1946-2017
010203019462016

Papers overview

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2015
2015
Phosphofructokinase-1 (PFK1), the ‘gatekeeper’ of glycolysis, catalyses the committed step of the glycolytic pathway by… (More)
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Highly Cited
2009
Highly Cited
2009
Neurons are known to have a lower glycolytic rate than astrocytes and when stressed they are unable to upregulate glycolysis… (More)
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Highly Cited
2008
Highly Cited
2008
6-phosphofructo-1-kinase, a rate-limiting enzyme of glycolysis, is activated in neoplastic cells by fructose-2,6-bisphosphate… (More)
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2003
2003
V-type or H+-ATPases are a family of ATP-dependent proton pumps that move protons across the plasma membrane at specialized sites… (More)
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Highly Cited
2003
Highly Cited
2003
The serine/threonine kinase Akt is a component of many receptor signal transduction pathways and can prevent cell death following… (More)
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Highly Cited
2000
Highly Cited
2000
Unlike normal mammalian cells, which use oxygen to generate energy, cancer cells rely on glycolysis for energy and are therefore… (More)
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1995
1995
The orally effective antidiabetic agent Troglitazone (CS-045) exerts hypoglycemic effects in various insulin-resistant obese and… (More)
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1992
1992
The influence of 6-phosphofructo-1-kinase on glycolytic flux in the yeast Saccharomyces cerevisiae was assessed by measuring the… (More)
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Highly Cited
1963
Highly Cited
1963
IN perfused rat heart, glycolysis is accelerated by anoxia and uncouplers of respiratory chain phosphorylation and inhibited by… (More)
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1947
1947
The methods available for the quantitative assay of these enzymes are based on phosphate transfer determinations and pH change of… (More)
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