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6-O-monoacetylmorphine

Known as: 6-MAM cpd, 6-Monoacetylmorphine, 6-acetylmorphine 
National Institutes of Health

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Related topics

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Broader (1)

Morphine Derivatives Including Cocaine

Papers overview

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Highly Cited
2012
Highly Cited
2012
Target screening and confirmation of 35 licit and illicit drugs and metabolites in hair by LC-MSMS.
Review
2006
Review
2006
Drug testing in oral fluid.
Over the last decade there have been considerable developments in the use of oral fluid (saliva) for drug testing. Oral fluid can… 
Highly Cited
1997
Highly Cited
1997
Purification and Cloning of a Broad Substrate Specificity Human Liver Carboxylesterase That Catalyzes the Hydrolysis of Cocaine and Heroin*
A human liver carboxylesterase (hCE-2) that catalyzes the hydrolysis of the benzoyl group of cocaine and the acetyl groups of 4… 
Highly Cited
1997
Highly Cited
1997
Influence of the cosmetic treatment of hair on drug testing
Abstract An important issue of concern for drug analysis in hair is the change in the drug concentration induced by the cosmetic… 
Highly Cited
1996
Highly Cited
1996
Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases.
Concomitant i.v. use of cocaine and heroin ("speedballing") is prevalent among drug-abusing populations. Heroin is rapidly… 
Highly Cited
1991
Highly Cited
1991
Forensic drug testing for opiates: I. Detection of 6-acetylmorphine in urine as an indicator of recent heroin exposure; drug and assay considerations and detection times.
The urinary excretion patterns of 6-acetylmorphine (6-AM), free morphine, and total morphine were determined by GC/MS assay for… 
Highly Cited
1988
Highly Cited
1988
Pharmacology of the allodynia in rats evoked by high dose intrathecal morphine.
Morphine sulfate in doses of 90 to 150 micrograms/3 microliters evoke a prominent behavioral syndrome characterized by 1… 
Highly Cited
1984
Highly Cited
1984
The Pharmacokinetics of Heroin in Patients with Chronic Pain
We measured blood concentrations of heroin and its active metabolites, 6-acetylmorphine and morphine, serially in 11 patients… 
Highly Cited
1983
Highly Cited
1983
Evidence from opiate binding studies that heroin acts through its metabolites.
Highly Cited
1980
Highly Cited
1980
Hydrolysis of diacetylmorphine (heroin) by human serum cholinesterase.
The enzyme in human serum that rapidly hydrolyzes diacetylmorphine (heroin) to 6-acetylmorphine is identified in this report as… 
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