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5-vinyluracil

Known as: 5-ethenyl-2,4(1H,3H)-pyrimidinedione 
National Institutes of Health

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2 relations

Broader (1)

Uracil
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Nucleic Acids Research
The promoter of the gene for the major outer membrane llpoprotein, the most abundant protein in Escherichia coll. is considered… 
2014
2014
Polymerase Synthesis of DNAs Bearing Vinyl Groups in the Major Groove and their Cleavage by Restriction Endonucleases
DNA molecules containing 5‐vinyluracil, 5‐vinylcytosine, or 7‐deaza‐7‐vinyladenine were prepared by polymerase incorporation of… 
2004
2004
Single Ascending Dose Tolerability, Pharmacokinetic–Pharmacodynamic Study of Dihydropyrimidine Dehydrogenase Inhibitor Ro 09-4889
Purpose: Ro 09-4889 was designed to enhance the anticancer efficacy of capecitabine (Xeloda) by generating a dihydropyrimidine… 
2003
2003
Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.
2003
2003
Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889
Capecitabine is an orally available fluoropyrimidine and is finally converted to 5‐FU selectively in tumor tissues. In our study… 
1980
1980
Incorporation of 5-substituted uracil derivatives into nucleic acids. The isolation and gamma-radiation-sensitivity of bacteriophage T3 containing the thymine analogue 5-vinyluracil.
Bacteriophage T3 was produced in a form that contained 32% of its normal DNA thymine residues replaced with 5-vinyluracil… 
1979
1979
The sensitivity of Mycoplasma mycoides var. capri cells to gamma-radiation after growth in a medium containing the thymine analogue 5-vinyluracil.
Cells of the bacterium Mycoplasma mycoides var. capri grown in a medium containing the potential radiation-sensitive thymine… 
1974
1974
A method for the rapid preparation of 5-vinyluracil in high yield.
A method for the rapid preparation of the thymineanalogue, 5-vinyluracil, in 83% yield from 5-(1-hydroxyethyl)uracil via the… 
1973
1973
The chemistry of some 5-(2-hydroxyalkyl)uracil derivatives and a synthesis of 5-vinyluracil.
1973
1973
Incorporation of 5-substituted uracil derivatives into nucleic acids. II. Incorporation of 5-vinyluracil into the DNA of Escherichia coli.
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