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5-methylurapidil

Known as: 5-methyl-urapidil 
National Institutes of Health

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2 relations

Broader (2)

Adrenergic alpha-AntagonistsPiperazines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Expression of distinct α1‐adrenoceptor phenotypes in the iris of pigmented and albino rabbits
Background and purpose:  The expression of multiple pharmacological phenotypes including α1L‐adrenoceptor has recently been… 
Highly Cited
2006
Highly Cited
2006
A comparative in vitro study to determine the beneficial effect of calcium‐channel and α1‐adrenoceptor antagonism on human ureteric activity
To compare the in vitro human ureteric muscle response to calcium‐channel and α‐adrenoceptor antagonists, to determine the… 
Highly Cited
2003
Highly Cited
2003
Doxazosin Induces Apoptosis in Cardiomyocytes Cultured In Vitro by a Mechanism That Is Independent of &agr;1-Adrenergic Blockade
Background—The &agr;1-adrenoceptor–blocking antihypertensive doxazosin has been associated with increased risk of heart failure… 
Highly Cited
2001
Highly Cited
2001
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes.
Binding affinities of serotonin (5-HT)-receptor antagonists and agonists at human recombinant alpha1-adrenoceptor subtypes… 
Highly Cited
2000
Highly Cited
2000
α1-Adrenoceptor subtypes in rat renal resistance vessels : In vivo and in vitro studies
This study provides new information about the relative importance of different α1-adrenoceptors during norepinephrine (NE… 
Highly Cited
2000
Highly Cited
2000
The alpha(1)-adrenoceptor subtype- and protein kinase C isoform-dependence of Norepinephrine's actions in cardiomyocytes.
Catecholamines modulate cardiac function at least in part through alpha(1)-adrenergic receptors linked to the activation of… 
1999
1999
Contractile responses to α1‐adrenoceptor agonists in isolated human male and female urethra
To investigate the contractile responses mediated through α1‐adrenoceptors in human urethra and to evaluate the effectiveness of… 
1997
1997
Effect of 5-methylurapidil, an alpha 1a-adrenergic antagonist and 5-hydroxytryptamine1a agonist, on aqueous humor dynamics in monkeys and rabbits.
PURPOSE To evaluate the effects of 5-methylurapidil (5-MU) on intraocular pressure (IOP) and aqueous humor dynamics in female… 
1993
1993
Pharmacological evidence for interactions between 5-HT1A receptor agonists and subtypes of alpha 1-adrenoceptors on rabbit aorta.
1992
1992
Cardiovascular effects of the 5-HT1A receptor ligand, MDL 73005EF, in conscious spontaneously hypertensive rats.
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