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Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma.
OBJECTIVE To explore the possibility that the excitatory amino acid glutamate might be associated with the disease process of glaucoma, which is characterized by the death of retinal ganglion cellExpand
Retinal damage after 3 to 4 months of elevated intraocular pressure in a rat glaucoma model.
PURPOSE To characterize a long-term elevated intraocular pressure (IOP) glaucoma model in the rat with respect to electroretinographic (ERG) changes and the pattern and mechanism of retinal ganglionExpand
Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA/2NNia glaucomatous mice: comparison with RGC loss in aging C57/BL6 mice.
PURPOSE To quantify the extent and pattern of retinal ganglion cell (RGC) loss in the DBA2/NNia glaucomatous mouse strain as a function of age and compare it with ganglion cell loss in aExpand
Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes.
PURPOSE Complement has been implicated in the pathogenesis of neurodegenerative diseases. The purpose of this study was to investigate whether complement activation is part of the pathogenesis ofExpand
Retinal morphology and ERG response in the DBA/2NNia mouse model of angle-closure glaucoma.
PURPOSE To document the time course of retinal dysfunction by scotopic electroretinography (ERG) and by quantitative morphology in eyes of the DBA/2NNia substrain of mouse (DBA) with inheritedExpand
Textbook of Ophthalmology
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Topographic and morphologic analyses of retinal ganglion cell loss in old DBA/2NNia mice.
PURPOSE To evaluate the relationship between retinal ganglion cell (RGC) size, density distribution, and survival in senescent DBA2/NNia mice that develop pigmentary glaucoma. To evaluate theExpand
Microbial contamination of medications used to treat glaucoma.
AIMS--A study was conducted to estimate the frequency of contamination of topical antiglaucoma medications used by asymptomatic patients. METHODS--The drops and the bottle tips of 194 in use topicalExpand
Lipid peroxidation in cataract of the human.
Lipid peroxidation was investigated as one of the possible mechanisms of cataractogenesis in the human. Malondialdehyde (MDA), a major breakdown product of lipid peroxides, was significantly higherExpand
Electroretinographic abnormalities in a rat glaucoma model with chronic elevated intraocular pressure.
The purpose of this study was to determine the ability of electroretinographic (ERG) measurements to document progression of the retinopathy in a rat glaucoma model. Thirty four rats with a chronicExpand