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5-hydroxymethyl-2'-deoxyuridine

Known as: 2'-deoxy-5-(hydroxymethyl)uridine, 5-hydroxymethyldeoxyuridine, alpha-hydroxythymidine 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Antineoplastic AgentsThymidine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung−/−Msh2−/− mice
Deamination of cytosine (C), 5-methylcytosine (mC) and 5-hydroxymethylcytosine (hmC) occurs spontaneously in mammalian DNA with… 
Highly Cited
2001
Highly Cited
2001
Effect of soy isoflavone supplementation on markers of oxidative stress in men and women.
Highly Cited
1998
Highly Cited
1998
Serum autoantibodies recognizing 5-hydroxymethyl-2'-deoxyuridine, an oxidized DNA base, as biomarkers of cancer risk in women.
Human sera contain anti-5-hydroxymethyl-2'-deoxyuridine (HMdU; an oxidized thymidine) autoantibodies (aAbs), which are… 
Highly Cited
1996
Highly Cited
1996
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153)
The gene encoding C/EBP-homologous protein (CHOP), also known as growth arrest and DNA-damage-inducible gene 153 (GADD153), is… 
Highly Cited
1996
Highly Cited
1996
Levels of 5‐hydroxymethyl‐2′‐deoxyuridine in DNA from blood as a marker of breast cancer
Oxidative DNA damage can result from numerous endogenous metabolic processes as well as from exposure to environmental and… 
Highly Cited
1995
Highly Cited
1995
7,12-dimethylbenz[a]anthracene induces oxidative DNA modification in vivo.
Highly Cited
1991
Highly Cited
1991
Quantitative high-performance liquid chromatography analysis of DNA oxidized in vitro and in vivo.
Highly Cited
1990
Highly Cited
1990
5-Formyldeoxyuridine: a new type of DNA damage induced by ionizing radiation and its mutagenicity to salmonella strain TA102.
1988
1988
Mutagenicity of 5-hydroxymethyl-2'-deoxyuridine to Chinese hamster cells.
5-Hydroxymethyluracil (HmUra) is formed from thymine in DNA through the action of ionizing radiation or reactive oxygen species… 
Highly Cited
1984
Highly Cited
1984
Ionizing radiation and tritium transmutation both cause formation of 5-hydroxymethyl-2'-deoxyuridine in cellular DNA.
HeLa cells grown in the presence of [methyl-3H]thymidine contained large amounts of 5-hydroxymethyl-2'-deoxyuridine (HMdU) in… 
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