5-hydroxymethyl-2'-deoxyuridine

We report an investigation into analogues of the thrombin binding aptamer (TBA). Individual thymidines were replaced by the… (More)

Systemic oxidative stress is thought to contribute to risk of various cancers, including breast cancer. DNA repair ability also… (More)

Human sera contain anti-5-hydroxymethyl-2'-deoxyuridine (HMdU; an oxidized thymidine) autoantibodies (aAbs), which are… (More)

BACKGROUND Oxidative DNA damage can result from numerous endogenous metabolic processes as well as from exposure to environmental… (More)

The gene encoding C/EBP-homologous protein (CHOP), also known as growth arrest and DNA-damage-inducible gene 153 (GADD153), is… (More)

DNA damage induced by oxidants includes formation of DNA strand breaks as well as oxidative damage to DNA bases. We quantified… (More)

5-Hydroxymethyluracil (HmUra) is formed from thymine in DNA through the action of ionizing radiation or reactive oxygen species… (More)

Ionizing radiation causes formation of heterogeneous types of damage to DNA. Among those, 5-hydroxymethyl-2'-deoxyuridine (HMdU… (More)

5-Hydroxymethyl-2'-deoxyuridine is an antileukemic thymidine analogue. It is also a well known thymidine-derivative in DNA… (More)

HeLa cells grown in the presence of [methyl-3H]thymidine contained large amounts of 5-hydroxymethyl-2'-deoxyuridine (HMdU) in… (More)