5-hydroxymethyl-2'-deoxyuridine

Deamination of cytosine (C), 5-methylcytosine (mC) and 5-hydroxymethylcytosine (hmC) occurs spontaneously in mammalian DNA with… Expand

Systemic oxidative stress is thought to contribute to risk of various cancers, including breast cancer. DNA repair ability also… Expand

Dietary intake of soy has been linked with decreased cancer risk, and the active compounds in soy that have been identified… Expand

Human sera contain anti-5-hydroxymethyl-2'-deoxyuridine (HMdU; an oxidized thymidine) autoantibodies (aAbs), which are… Expand

Curcumin (diferuloylmethane), the naturally occurring yellow pigment in turmeric and curry, is isolated from the rhizomes of the… Expand

The gene encoding C/EBP-homologous protein (CHOP), also known as growth arrest and DNA-damage-inducible gene 153 (GADD153), is… Expand

Oxidative DNA damage can result from numerous endogenous metabolic processes as well as from exposure to environmental and… Expand

An aqueous solution of calf thymus DNA was irradiated by 60Co gamma-rays and modified nucleosides produced in DNA were analyzed… Expand

Ionizing radiation causes formation of heterogeneous types of damage to DNA. Among those, 5-hydroxymethyl-2'-deoxyuridine (HMdU… Expand

HeLa cells grown in the presence of [methyl-3H]thymidine contained large amounts of 5-hydroxymethyl-2'-deoxyuridine (HMdU) in… Expand