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5-hydroxymethyl-2'-deoxyuridine
Known as:
2'-deoxy-5-(hydroxymethyl)uridine
, 5-hydroxymethyldeoxyuridine
, alpha-hydroxythymidine
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Antineoplastic Agents
Thymidine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
J‐binding protein increases the level and retention of the unusual base J in trypanosome DNA
M. Cross
,
R. Kieft
,
R. Sabatini
,
A. Dirks‐Mulder
,
I. Chaves
,
P. Borst
Molecular Microbiology
2002
Corpus ID: 34692526
The nuclear DNA of Trypanosoma brucei and other kinetoplastid flagellates contains the unusual base β‐d‐glucosyl…
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2001
2001
Levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from blood of women scheduled for breast biopsy.
Zora Djuric
,
L. Heilbrun
,
Samir Lababidi
,
Egle Berzinkas
,
Michael S. Simon
,
M. Kosir
Cancer Epidemiology, Biomarkers and Prevention
2001
Corpus ID: 7685691
Systemic oxidative stress is thought to contribute to risk of various cancers, including breast cancer. DNA repair ability also…
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1999
1999
Alpha-tocopherol dietary supplement decreases titers of antibody against 5-hydroxymethyl-2'-deoxyuridine (HMdU).
J. Hu
,
C. Chi
,
+5 authors
R. D'Agostino
Cancer Epidemiology, Biomarkers and Prevention
1999
Corpus ID: 46269490
This study evaluated the effects of vitamin E (alpha-tocopherol) on oxidative DNA damage in a randomized double-blind Phase II…
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1993
1993
Recognition of oxidized DNA bases by sera of patients with inflammatory diseases.
K. Frenkel
,
J. Karkoszka
,
E. Kim
,
E. Taioli
Free Radical Biology & Medicine
1993
Corpus ID: 32484844
1990
1990
Formation of 5-hydroxymethyl-2'-deoxyuridine in hepatic DNA of rats treated with gamma-irradiation, diethylnitrosamine, 2-acetylaminofluorene or the peroxisome proliferator ciprofibrate.
S. Srinivasan
,
H. Glauert
Carcinogenesis
1990
Corpus ID: 22521009
The peroxisome proliferator ciprofibrate was tested for its ability to induce DNA damage in the form of 5-hydroxymethyl-2…
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1989
1989
Effect of metals on nucleoside hydroperoxide, a product of ionizing radiation in DNA.
S. Tofigh
,
K. Frenkel
Free Radical Biology & Medicine
1989
Corpus ID: 24203157
1989
1989
Effects of 5-hydroxymethyluracil and 3-aminobenzamide on the repair and toxicity of 5-hydroxymethyl-2'-deoxyuridine in mammalian cells.
R. Boorstein
,
G. Teebor
Cancer Research
1989
Corpus ID: 40804076
5-Hydroxymethyl-2'-deoxyuridine (HmdUrd), a cytotoxic analogue of thymidine, has been proposed for use as an anticancer agent…
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1988
1988
Mutagenicity of 5-hydroxymethyl-2'-deoxyuridine to Chinese hamster cells.
R. Boorstein
,
G. Teebor
Cancer Research
1988
Corpus ID: 21880608
5-Hydroxymethyluracil (HmUra) is formed from thymine in DNA through the action of ionizing radiation or reactive oxygen species…
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1988
1988
Metabolism, incorporation into DNA, and interactions with 1-beta-D-arabinofuranosylcytosine of 5-hydroxymethyl-2'-deoxyuridine in human promyelocytic leukemia cells (HL-60).
J. Vilpo
,
L. Vilpo
Cancer Research
1988
Corpus ID: 13487571
5-Hydroxymethyl-2'-deoxyuridine (5HmdUrd) and 1-beta-D-arabinofuranosylcytosine (Ara-C) had a dose-dependent synergistic or…
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1985
1985
5-Hydroxymethyl-2'-deoxyuridine. Cytotoxicity and DNA incorporation studied by using a novel [2-14C]-derivative with normal and leukemic human hematopoietic cells.
L. Kahilainen
,
D. Bergstrom
,
J. Vilpo
Acta chemica Scandinavica. Series B: Organic…
1985
Corpus ID: 34790003
5-Hydroxymethyl-2'-deoxyuridine is a biologically active thymidine analogue. This investigation was aimed at characterizing the…
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