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5-hydroxymethyl-2'-deoxyuridine
Known as:
2'-deoxy-5-(hydroxymethyl)uridine
, 5-hydroxymethyldeoxyuridine
, alpha-hydroxythymidine
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Antineoplastic Agents
Thymidine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung−/−Msh2−/− mice
K. Kemmerich
,
Felix A Dingler
,
C. Rada
,
M. Neuberger
Nucleic Acids Research
2012
Corpus ID: 8970522
Deamination of cytosine (C), 5-methylcytosine (mC) and 5-hydroxymethylcytosine (hmC) occurs spontaneously in mammalian DNA with…
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Highly Cited
2001
Highly Cited
2001
Effect of soy isoflavone supplementation on markers of oxidative stress in men and women.
Z. Djuric
,
G. Chen
,
D. Doerge
,
L. Heilbrun
,
O. Kucuk
Cancer Letters
2001
Corpus ID: 28852076
Highly Cited
1998
Highly Cited
1998
Serum autoantibodies recognizing 5-hydroxymethyl-2'-deoxyuridine, an oxidized DNA base, as biomarkers of cancer risk in women.
K. Frenkel
,
J. Karkoszka
,
+5 authors
I. Kato
Cancer Epidemiology, Biomarkers and Prevention
1998
Corpus ID: 34552908
Human sera contain anti-5-hydroxymethyl-2'-deoxyuridine (HMdU; an oxidized thymidine) autoantibodies (aAbs), which are…
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Highly Cited
1996
Highly Cited
1996
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153)
X. Wang
,
B. Lawson
,
+7 authors
D. Ron
Molecular and Cellular Biology
1996
Corpus ID: 46719407
The gene encoding C/EBP-homologous protein (CHOP), also known as growth arrest and DNA-damage-inducible gene 153 (GADD153), is…
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Highly Cited
1996
Highly Cited
1996
Levels of 5‐hydroxymethyl‐2′‐deoxyuridine in DNA from blood as a marker of breast cancer
Z. Djuric
,
L. Heilbrun
,
+4 authors
S. Martino
Cancer
1996
Corpus ID: 22999884
Oxidative DNA damage can result from numerous endogenous metabolic processes as well as from exposure to environmental and…
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Highly Cited
1995
Highly Cited
1995
7,12-dimethylbenz[a]anthracene induces oxidative DNA modification in vivo.
K. Frenkel
,
L. Wei
,
H. Wei
Free Radical Biology & Medicine
1995
Corpus ID: 8710112
Highly Cited
1991
Highly Cited
1991
Quantitative high-performance liquid chromatography analysis of DNA oxidized in vitro and in vivo.
K. Frenkel
,
Z. Zhong
,
+5 authors
J. Solomon
Analytical Biochemistry
1991
Corpus ID: 23173188
Highly Cited
1990
Highly Cited
1990
5-Formyldeoxyuridine: a new type of DNA damage induced by ionizing radiation and its mutagenicity to salmonella strain TA102.
H. Kasai
,
A. Iida
,
Z. Yamaizumi
,
S. Nishimura
,
H. Tanooka
Mutation research
1990
Corpus ID: 30197532
1988
1988
Mutagenicity of 5-hydroxymethyl-2'-deoxyuridine to Chinese hamster cells.
R. Boorstein
,
G. Teebor
Cancer Research
1988
Corpus ID: 21880608
5-Hydroxymethyluracil (HmUra) is formed from thymine in DNA through the action of ionizing radiation or reactive oxygen species…
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Highly Cited
1984
Highly Cited
1984
Ionizing radiation and tritium transmutation both cause formation of 5-hydroxymethyl-2'-deoxyuridine in cellular DNA.
G. Teebor
,
K. Frenkel
,
M. S. Goldstein
Proceedings of the National Academy of Sciences…
1984
Corpus ID: 34326801
HeLa cells grown in the presence of [methyl-3H]thymidine contained large amounts of 5-hydroxymethyl-2'-deoxyuridine (HMdU) in…
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